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November 2015 CoverNovember 2015 | Volume 123 | Issue 11

On the Cover

Although heat waves and cold snaps pose major health risks and grab headlines when they occur, recent studies have uncovered a more complex and perhaps unexpected relationship between temperature and public health.

© John Myers/Getty

November 2015 | Volume 123 | Issue 11


Between Extremes: Health Effects of Heat and Cold

Nate Seltenrich | A275

Outbreak Breakthrough: Using Whole-Genome Sequencing to Control Hospital Infection

Carrie Arnold | A281

Time and Temperature: Changes in Heat-Related Mortality over 27 Years

Wendee Nicole | A287

Also see Gasparrini et al., p. 1200

Bias in Environmental Cohort Studies: The Example of Bone Lead and Mortality

Carol Potera | A288

Also see Weisskopf et al., p. 1113


Interweaving Knowledge Resources to Address Complex Environmental Health Challenges

Beth Ellen Anderson, Marisa F. Naujokas, and William A. Suk | 1095

Social Science Collaboration with Environmental Health

Elizabeth Hoover, Mia Renauld, Michael R. Edelstein, and Phil Brown | 1100


Lung Cancer and Exposure to Nitrogen Dioxide and Traffic: A Systematic Review and Meta-Analysis

Ghassan B. Hamra, Francine Laden, Aaron J. Cohen, Ole Raaschou-Nielsen, Michael Brauer, and Dana Loomis | 1107

Biased Exposure–Health Effect Estimates from Selection in Cohort Studies: Are Environmental Studies at Particular Risk?

Marc G. Weisskopf, David Sparrow, Howard Hu, and Melinda C. Power | 1113

Also see Science Selections, p. A288


Association of Parkinson’s Disease and Its Subtypes with Agricultural Pesticide Exposures in Men: A Case–Control Study in France

Frédéric Moisan, Johan Spinosi, Laurène Delabre, Véronique Gourlet, Jean-Louis Mazurie, Isabelle Bénatru, Marcel Goldberg, Marc G. Weisskopf, Ellen Imbernon, Christophe Tzourio, and Alexis Elbaz | 1123

Predictors of Indoor Radon Concentrations in Pennsylvania, 1989–2013

Joan A. Casey, Elizabeth L. Ogburn, Sara G. Rasmussen, Jennifer K. Irving, Jonathan Pollak, Paul A. Locke, and Brian S. Schwartz | 1130

Arsenic Exposure and Glucose Intolerance/Insulin Resistance in Estrogen-Deficient Female Mice

Chun-Fa Huang, Ching-Yao Yang, Ding-Cheng Chan, Ching-Chia Wang, Kuo-How Huang, Chin-Ching Wu, Keh-Sung Tsai, Rong-Sen Yang, and Shing-Hwa Liu | 1138

An Assessment of Participatory Integrated Vector Management for Malaria Control in Kenya

Clifford Maina Mutero, Charles Mbogo, Joseph Mwangangi, Susan Imbahale, Lydia Kibe, Benedict Orindi, Melaku Girma, Annah Njui, Wilber Lwande, Hippolyte Affognon, Charity Gichuki, and Wolfgang Richard Mukabana | 1145

Ambient Coarse Particulate Matter and Hospital Admissions in the Medicare Cohort Air Pollution Study, 1999–2010

Helen Powell, Jenna R. Krall, Yun Wang, Michelle L. Bell, and Roger D. Peng | 1152

Identification of Microcystis aeruginosa Peptides Responsible for Allergic Sensitization and Characterization of Functional Interactions between Cyanobacterial Toxins and Immunogenic Peptides

Esmond N. Geh, Debajyoti Ghosh, Melanie McKell, Armah A. de la Cruz, Gerard Stelma, and Jonathan A. Bernstein | 1159

Satellite-Based Estimates of Long-Term Exposure to Fine Particles and Association with Mortality in Elderly Hong Kong Residents

Chit Ming Wong, Hak Kan Lai, Hilda Tsang, Thuan Quoc Thach, G. Neil Thomas, Kin Bong Hubert Lam, King Pan Chan, Lin Yang, Alexis K.H. Lau, Jon G. Ayres, Siu Yin Lee, Wai Man Chan, Anthony J. Hedley, and Tai Hing Lam | 1167

Dietary Supplementation with Olive Oil or Fish Oil and Vascular Effects of Concentrated Ambient Particulate Matter Exposure in Human Volunteers

Haiyan Tong, Ana G. Rappold, Melissa Caughey, Alan L. Hinderliter, Maryann Bassett, Tracey Montilla, Martin W. Case, Jon Berntsen, Philip A. Bromberg, Wayne E. Cascio, David Diaz-Sanchez, Robert B. Devlin, and James M. Samet | 1173

Ambient PM2.5, O3, and NO2 Exposures and Associations with Mortality over 16 Years of Follow-Up in the Canadian Census Health and Environment Cohort (CanCHEC)

Dan L. Crouse, Paul A. Peters, Perry Hystad, Jeffrey R. Brook, Aaron van Donkelaar, Randall V. Martin, Paul J. Villeneuve, Michael Jerrett, Mark S. Goldberg, C. Arden Pope III, Michael Brauer, Robert D. Brook, Alain Robichaud, Richard Menard, and Richard T. Burnett | 1180

Spatial Variation and Land Use Regression Modeling of the Oxidative Potential of Fine Particles

Aileen Yang, Meng Wang, Marloes Eeftens, Rob Beelen, Evi Dons, Daan L.A.C. Leseman, Bert Brunekreef, Flemming R. Cassee, Nicole A.H. Janssen, and Gerard Hoek | 1187

Identification and Prioritization of Relationships between Environmental Stressors and Adverse Human Health Impacts

Shannon M. Bell and Stephen W. Edwards | 1193

Temporal Variation in Heat–Mortality Associations: A Multicountry Study

Antonio Gasparrini, Yuming Guo, Masahiro Hashizume, Patrick L. Kinney, Elisaveta P. Petkova, Eric Lavigne, Antonella Zanobetti, Joel D. Schwartz, Aurelio Tobias, Michela Leone, Shilu Tong, Yasushi Honda, Ho Kim, and Ben G. Armstrong | 1200

Also see Science Selections, p. A287

Children’s Health

Ambient Air Pollution and Newborn Size and Adiposity at Birth: Differences by Maternal Ethnicity (the Born in Bradford Study Cohort)

Anna Schembari, Kees de Hoogh, Marie Pedersen, Payam Dadvand, David Martinez, Gerard Hoek, Emily S. Petherick, John Wright, and Mark J. Nieuwenhuijsen | 1208

Prepubertal Serum Concentrations of Organochlorine Pesticides and Age at Sexual Maturity in Russian Boys

Thuy Lam, Paige L. Williams, Mary M. Lee, Susan A. Korrick, Linda S. Birnbaum, Jane S. Burns, Oleg Sergeyev, Boris Revich, Larisa M. Altshul, Donald G. Patterson Jr., and Russ Hauser | 1216


Brief Communication

Lessons from Toxicology: Developing a 21st-Century Paradigm for Medical Research

Gill Langley, Christopher P. Austin, Anil K. Balapure, Linda S. Birnbaum, John R. Bucher, Julia Fentem, Suzanne C. Fitzpatrick, John R. Fowle III, Robert J. Kavlock, Hiroaki Kitano, Brett A. Lidbury, Alysson R. Muotri, Shuang-Qing Peng, Dmitry Sakharov, Troy Seidle, Thales Trez, Alexander Tonevitsky, Anja van de Stolpe, Maurice Whelan, and Catherine Willett | A268


Comment on “Predictors of Indoor Radon Concentrations in Pennsylvania, 1989–2013”

Terry Engelder | A273

Response to “Comment on ‘Predictors of Indoor Radon Concentrations in Pennsylvania, 1989–2013’”

Joan A. Casey, Sara G. Rasmussen, and Brian S. Schwartz | A273

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