Editorial Volume 121 | Issue 9 | September 2013
EHP Classic Paper of the Year, 2013
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Environmental Health Perspectives (EHP) established the Paper of the Year in 2008 (Tilson 2008) as a way of highlighting high-quality articles published in the journal. The EHP Classic Paper of the Year is given to the most highly cited Research Article, Commentary, or Review Article over the preceding 60 months. We are proud to announce that the 2013 EHP Classic Paper of the Year is “Effects of Particulate Matter on Genomic DNA Methylation Content and iNOS Promoter Methylation” by Letizia Tarantini, Matteo Bonzini, Pietro Apostoli, Valeria Pegoraro, Valentina Bollati, Barbara Marinelli, Laura Cantone, Giovanna Rizzo, Lifang Hou, Joel Schwartz, Pier Alberto Bertazzi, and Andrea Baccarelli, published in the February 2009 issue of EHP.
Tarantini et al. (2009) investigated molecular mechanisms underlying health effects of particulate matter exposures using biomarkers of DNA methylation that reflect reprogramming of gene expression. Their 2009 publication was one of the first to report application of epigenetic markers in an environmental or occupational health context.
This research has had a significant influence on human environmental health research. The study by Tarantini et al. (2009) was one of the first studies to report evidence that DNA methylation may be altered in response to short-term exposures, and that it may reflect effects of usual levels of exposure over longer periods of time as well. This study also showed that easy-to-collect biospecimens, such as whole blood samples, and stored archival samples could be used to study effects of exposures on the epigenome. Novel laboratory and statistical approaches used in the study have since become routine in research on the epigenetic effects of environmental agents.
EHP congratulates Tarantini and colleagues for their sustained contribution to the environmental health science literature. They should be recognized for their outstanding contribution to the rapidly evolving field of environmental epigenetics.
Tarantini L, Bonzini M, Apostoli P, Pegoraro V, Bollati V, Marinelli B, et al. 2009. Effects of particulate matter on genomic DNA methylation content and iNOS promoter methylation. Environ Health Perspect 117:217–222; doi:10.1289/ehp.11898.
Tilson H. 2008. EHP papers of the year, 2008. Environ Health Perspect 116:A234; doi:10.1289/ehp.11684.
EHP is pleased to present the abstracts from the 28th annual meeting of the International Society for Environmental Epidemiology (ISEE), held in Rome, Italy, 1–4 September 2016, and hosted by the Department of Epidemiology Lazio Regional Health Service, ASL Roma 1, and the Italian Epidemiological Association. The focus of this year’s conference is current and future challenges in exposure assessment, study design, and data analyses.
For a number of years, EHP has posted accepted manuscripts online as what we termed Advance Publications. The concept here was simple—to get the content online as quickly as possible in an effort both to get authors the attention they deserve and to get readers the information they need. This product has served our community well, but it is not without its flaws. … MORE
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