Children's Health Advance Publication
Environ Health Perspect; DOI:10.1289/ehp.1510514
Reducing Phthalate, Paraben, and Phenol Exposure from Personal Care Products in Adolescent Girls: Findings from the HERMOSA Intervention Study
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Background: Personal care products are a source of exposure to potentially endocrine disrupting chemicals such as phthalates, parabens, triclosan, and benzophenone-3 (BP-3) for adolescent girls.
Methods: We enrolled 100 Latina girls in a youth-led, community-based participatory research intervention study to determine whether using personal care products whose labels stated they did not contain these chemicals for three days could lower urinary concentrations. Pre- and post-intervention urine samples were analyzed for phthalate metabolites, parabens, triclosan and BP-3 using high-performance liquid chromatography/tandem mass spectrometry.
Results: Urinary concentrations of mono-ethyl phthalate (MEP) decreased by 27.4% (95% Confidence Interval (CI): -39.3, -13.2) on average over the 3 day intervention; no significant changes were seen in urinary concentrations of mono-n-butyl phthalate (MnBP) and mono-isobutyl phthalate (MiBP). Methyl and propyl paraben concentrations decreased by 43.9% (95% CI: -61.3, -18.8) and 45.4% (95% CI: -63.7, -17.9), respectively. Unexpectedly, concentrations of ethyl and butyl paraben concentrations increased, although concentrations were low overall and not detected in almost half the samples. Triclosan concentrations decreased by 35.7% (95% CI: -53.3, -11.6) and BP-3 concentrations decreased by 36.0% (95% CI: -51.0, -16.4).
Discussion: This study demonstrates that techniques available to consumers, such as choosing personal care products that are labelled to be free of phthalates, parabens, triclosan, and BP-3, can reduce personal exposure to possible endocrine disrupting chemicals. Involving youth in the design and implementation of the study was key to recruitment, retention, compliance, and acceptability of the intervention.
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Citation: Harley KG, Kogut K, Madrigal DS, Cardenas M, Vera IA, Meza-Alfaro G, She J, Gavin Q, Zahedi R, Bradman A, Eskenazi B, Parra KL. Reducing Phthalate, Paraben, and Phenol Exposure from Personal Care Products in Adolescent Girls: Findings from the HERMOSA Intervention Study. Environ Health Perspect; http://dx.doi.org/10.1289/ehp.1510514
Received: 20 July 2015
Accepted: 18 February 2016
Advance Publication: 7 March 2016
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EHP is pleased to present the abstracts from the 28th annual meeting of the International Society for Environmental Epidemiology (ISEE), held in Rome, Italy, 1–4 September 2016, and hosted by the Department of Epidemiology Lazio Regional Health Service, ASL Roma 1, and the Italian Epidemiological Association. The focus of this year’s conference is current and future challenges in exposure assessment, study design, and data analyses.
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