April 2013 | Volume 121 | Issue 4
Lyme disease is the most common vectorborne infection in North America, and the ecology of the causative agent, a spirochete named Borrelia burgdorferi, is the subject of both intense study and intense scientific debate. Some researchers think protecting large tracts of forest habitat will ultimately reduce the risk of human infection. Others believe the relationship between host biodiversity and human disease risk is not so clearcut.
Spheres of Influence
The Federal Food, Drug, and Cosmetic (FD&C) Act of 1938 has been amended over the years in attempts to streamline and bring order to the sprawling task of assessing and categorizing the thousands of substances used in foods, drugs, and cosmetics. One result of this streamlining is that under current U.S. law, companies can add certain types of ingredients to foods without premarket approval from the Food and Drug Administration (FDA). Is this a problem? The answer depends on whom you ask.
Unclear Relationship: Prenatal but Not Concurrent Bisphenol A Exposure Linked to Lower Weight and Less Fat
Toward Primary Prevention of Cancer: The Case for a Global Strategy to Limit Environmental and Occupational Exposures
Climate Change, Human Health, and Biomedical Research: Analysis of the National Institutes of Health Research Portfolio
Environmental and Occupational Interventions for Primary Prevention of Cancer: A Cross-Sectorial Policy Framework
Arsenic Exposure from Drinking Water and QT-Interval Prolongation: Results from the Health Effects of Arsenic Longitudinal Study
The Natural Estrogenic Compound Diarylheptanoid (D3): In Vitro Mechanisms of Action and in Vivo Uterine Responses via Estrogen Receptor α
Biotransformation of BDE‑47 to Potentially Toxic Metabolites Is Predominantly Mediated by Human CYP2B6
Association of Osteoarthritis with Perfluorooctanoate and Perfluorooctane Sulfonate in NHANES 2003–2008
Associations of in Utero Exposure to Perfluorinated Alkyl Acids with Human Semen Quality and Reproductive Hormones in Adult Men
Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes
Polymorphisms in Iron Homeostasis Genes and Urinary Cadmium Concentrations among Nonsmoking Women in Argentina and Bangladesh
Performance in Omics Analyses of Blood Samples in Long-Term Storage: Opportunities for the Exploitation of Existing Biobanks in Environmental Health Research
Gestational Diabetes and Preeclampsia in Association with Air Pollution at Levels below Current Air Quality Guidelines
Urban Tree Canopy and Asthma, Wheeze, Rhinitis, and Allergic Sensitization to Tree Pollen in a New York City Birth Cohort
Race/Ethnicity–Specific Associations of Urinary Phthalates with Childhood Body Mass in a Nationally Representative Sample
Serum Polyfluoroalkyl Concentrations, Asthma Outcomes, and Immunological Markers in a Case–Control Study of Taiwanese Children
Maria Neira, R. Thomas Zoeller, Georg Becher, Poul Bjerregaard, Riana Bornman, Ingvar Brandt,
Andreas Kortenkamp, Derek Muir, Marie-Noël Brune Drisse, Roseline Ochieng, Niels E. Skakkebaek,
Agneta Sundén Byléhn, Taisen Iguchi, Jorma Toppari, and Tracey J. Woodruff | A104
Erratum: Perfluorooctanoic Acid Concentrations for Participants in the C8 Health Project [119(12):1760–1765 (2011)]
Erratum: Braun et al. “Variability of Urinary Phthalate Metabolite and Bisphenol A Concentrations before and during Pregnancy” [120:739–745 (2012)]
My Journal Shelf
EHP is now available on My Journal Shelf, a pilot project of the National Institute of Allergy and Infectious Diseases (NIAID) to provide quick access to current issues of scientific journals. Learn more about My Journal Shelf from NIAID.
EHP is proud to announce its 2013 Paper of the Year is “450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy” [Environ Health Perspect 120(10):1425–1431 (2012); doi:10.1289/ehp.1205412]. The Paper of the Year award is given to the most highly cited Research Article, Commentary, or Review Article published in the preceding 12 months.
Congratulations to authors Bonnie R. Joubert, Siri E. Håberg, Roy M. Nilsen, Xuting Wang, Stein E. Vollset, Susan K. Murphy, Zhiqing Huang, Cathrine Hoyo, Øivind Midttun, Lea A. Cupul-Uicab, Per M. Ueland, Michael C. Wu, Wenche Nystad, Douglas A. Bell, Shyamal D. Peddada, and Stephanie J. London.
Children’s Health Collection 2013 is now available for browsing and downloading. The collection includes everything we've published on children's health from October 2012 through September 2013—you'll find abstracts of peer-reviewed research articles, reviews, and commentaries, plus quick links to relevant news articles, editorials, and podcasts.
Environment and Health—
Bridging South, North, East and West
Basel, Switzerland 19–23 August 2013
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Recent Advance Publications
- Diethylstilbestrol (DES)-Stimulated Hormonal Toxicity is Mediated by ERα Alteration of Target Gene Methylation Patterns and Epigenetic Modifiers (DNMT3A, MBD2, and HDAC2) in the Mouse Seminal Vesicle
- Anogenital Distance and Penile Length in Infants with Hypospadias or Cryptorchidism: Comparison with Normative Data
- DNA Methylation in Oocytes and Liver of Female Mice and Their Offspring: Effects of High-Fat-Diet–Induced Obesity
- Environmental Noise Pollution in the United States: Developing an Effective Public Health Response
- Enablers and Barriers to Large-Scale Uptake of Improved Solid Fuel Stoves: A Systematic Review
- Breastfeeding: A Potential Excretion Route for Mothers and Implications for Infant Exposure to Perfluoroalkyl Acids
- Polyfluoroalkyl Chemicals and Menopause among Women 20-65 Years of Age (NHANES)
- EHPNoonNews: RaleighN&O—NC fracking commission considers putting chemical data in 'electronic lock box' http://t.co/WDyoXNMPZK
- EHPNoonNews: SouthChinaMorningPost—Phone app to provide real-time local air pollution levels http://t.co/eTDmKdxAMX
- EHPNoonNews: MilwaukeeJournalSentinel—CAFO manure spills reach 7-yr high in Wisconsin http://t.co/0B0B2XEOJJ
- EHPNoonNews: CBSNews—CDC releases results of Camp Lejeune tap water study http://t.co/MRsKPTGsTz
- Trending EHP news this week: Urban gardening: managing the risks of contaminated soil http://t.co/zw0j6x2JCd