The evaluation of chemical mutagenicity data in relation to population risk: impact of various types of genetic damage and risk assessment
Crow-JF
p. 1
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The evaluation of chemical mutagenicity data in relation to population risk: the need for better methods of extrapolation
Friedman-L
p. 7
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Evaluation of chromosome aberration effects of chemicals on mouse germ cells
Generoso-WM
p. 13
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Use of the dominant-lethal test to detect genetic activity of environmental chemicals
Epstein-SS
p. 23
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Some primary considerations in the interpretation of the dominant-lethal assay
Ray-VA; Hyneck-ML
p. 27
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The dominant-lethal test: potential limitations and statistical considerations for safety evaluation
Green-S; Springer-JA
p. 37
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Considerations for evaluating chemical mutagenicity to germinal cells
Maxwell-WA; Newell-GW
p. 47
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Statistical considerations for dominant lethal mutagenic trials
Salsburg-DS
p. 51
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Possible role of the blood-testicular barrier in dominant lethal testing
Dixon-RL; Lee-IP
p. 59
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The evaluation of chemical mutagenicity data in relation to population risk: summary of panel on the dominant-lethal test
Ray-V
p. 65
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Pharmacokinetic and other factors related to mutagenicity testing: quantitative analysis of the testing procedures
Rall-DP
p. 67
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In vitro versus in vivo metabolic activation of mutagens
Malling-HV; Frantz-CN
p. 71
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New developments in mutagenicity screening techniques with yeast
Brusick-DJ; Mayer-VW
p. 83
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Development of mutagen-sensitive strains of Neurospora to detect specific locus mutations
De-Serres-FJ
p. 97
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The evaluation of chemical mutagenicity data in relation to population risk: some factors affecting the host-mediated assay response
Zeiger-E
p. 101
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Note on Drosophila as a mutagenicity test system
Zimmering-S
p. 111
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Carcinogens are mutagens: their detection and classification
Ames-BN
p. 115
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Recent developments with the L5178Y TK heterozygote mutagen assay system
Clive-D
p. 119
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Mutation studies with human fibroblasts
DeMars-R
p. 127
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Use of the asparagine auxotroph of the L5178Y murine leukemia for the detection of chemical mutagens in vitro and in the host-mediated assay
Capizzi-RL; Summers-WP; Papirmeister-B
p. 137
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Current status of the host-mediated L5178Y system for detecting chemical mutagens
Lee-SY
p. 145
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Uses of banding techniques for the identification of human diseases of cytogenetic origin
Shaw-MW
p. 151
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Chromosome aberrations as a measure of mutagenesis: comparisons in vitro and in vivo and in somatic and germ cells
Brewen-JG; Preston-RJ
p. 157
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The micronucleus test as an in vivo cytogenetic method
Miller-RC
p. 167
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Thresholds in toxic, teratogenic, mutagenic, and carcinogenic effects
Freese-E
p. 171
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Significance of various type chromosome aberrations for man
Nichols-WW
p. 179
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Leukemia and the somatic risks of chemical mutagens
Lewis-EB
p. 185
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Practical aspects of mutagenicity testing
Ramel-C
p. 191
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Comments on and summary of panel on assessment of in vitro and in vivo mutagenicity data with regard to safety evaluation
Abramamson-S
p. 193
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Chemical dosimetry in somatic cells and its utility to mutagenesis
Patterson-JB
p. 195
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An approach to measuring germinal mutations in the mouse
Valcovic-LR; Malling-HV
p. 201
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A potential hazard: explosive production of mutations by induction of mutators
Morgan-K; Hastings-PJ; Borstel-RC-von
p. 207
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Pleiotropy and the detection of point mutations in the mammal
Wolff-GL
p. 211
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The role of repair in environmental mutagenesis
Flamm-WG
p. 215
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Some general principles of mutagenicity screening and a possible framework for testing procedures
Bridges-BA
p. 221
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General summary and recommendations for workshop on the evaluation of chemical mutagenicity data in relation to population risk
Hollaender A
p. 229
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Letter: Analyzing for organic mercurials by gas chromatography
Albro-PW; Latimer AD
p. 233
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