| Marine Algal Toxins: Origins, Health Effects, and Their Increased Occurrence Cynthia Carey Department of Environmental, Population, and Organismic Biology, University of Colorado, Boulder, Colorado USA Abstract
Many populations of amphibians are declining on all six continents on which they occur. Some causes of amphibian declines, such as habitat destruction, direct application of xenobiotics, and introduction of predators or competitors, are clearly attributable to human activities. Infectious disease appears to be the direct cause of mass amphibian die-offs in relatively undisturbed areas of the world where anthropomorphic environmental disruption is minimal. In these cases, it is not yet clear whether these epizootics result from the natural evolution of new pathogens or from environmental changes that promote the emergence of pathogenic forms and/or that weaken the immune defenses of amphibians. Because some aspects of pathogen-related amphibian mass mortalities are similar to outbreaks of new diseases in humans and coral reef organisms, amphibian declines may be part of a much larger pattern than previously appreciated. Key words: amphibians, amphibian declines, amphibian immune system, antimicrobial peptides, chytrid fungi, climate change, coral reefs, emerging diseases, ranaviruses, ultraviolet light. -- Environ Health Perspect 108(suppl 1) :143-150 (2000) . http://ehpnet1.niehs.nih.gov/docs/2000/suppl-1/143-150carey/abstract.html
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