News | Science Selections October 2016 | Volume 124 | Issue 10
Phthalates in Fast Food: A Potential Dietary Source of Exposure
Wendee Nicole was awarded the inaugural Mongabay Prize for Environmental Reporting in 2013. She writes for Discover, Scientific American, National Wildlife, and other magazines.
Citation: Nicole W. 2016. Phthalates in fast food: a potential dietary source of exposure. Environ Health Perspect 124:A191; http://dx.doi.org/10.1289/ehp.124-A191
Published: 1 October 2016
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Related EHP Article
Recent Fast Food Consumption and Bisphenol A and Phthalates Exposures among the U.S. Population in NHANES, 2003–2010
Many research studies have surveyed nutritional habits, but fewer have studied how food processing and packaging might introduce unwanted chemicals into foods. In this issue of EHP, researchers report that fast food consumption appears to be one source of exposure to the chemicals di(2-ethylhexyl) phthalate (DEHP) and diisononyl phthalate (DiNP).1
The authors used data from the National Health and Nutrition Examination Survey (NHANES) to estimate the percentage of individuals’ calories that came from fast food, fat intake attributable to fast food consumption, and fast food intake by food group. During NHANES interviews, respondents had reported their diet from the preceding 24 hours. Fast food was defined as food obtained from restaurants without waiter service and from pizza restaurants, as well as all carryout and delivery food.2 Regression analyses were used to determine associations between fast food consumption and urinary concentrations of DEHP metabolites, DiNP metabolites, and bisphenol A (BPA).
NHANES data indicate that non-Hispanic blacks are more likely than other racial/ethnic groups to eat fast food. This raises questions about disproportionate exposures to phthalates found in fast food.
© Finbarr O’Reilly/Reuters
The final study population included nearly 9,000 people aged 6 years or older. Approximately one-third of people surveyed had eaten fast food in the preceding 24 hours. Study participants who ate fast food were more likely to be male, under age 40, and non-Hispanic black, and to have higher total calorie and total fat intake from fast food, compared with the general population.1
Fast food consumers had higher urinary levels of DEHP, DiNP, and BPA than non-consumers, although the differences in average urinary levels were small and for BPA were non-significant. When fast food intake was categorized by food group, DEHP metabolites were associated with intake of grains and “other” (a category that included vegetables, condiments, potato items, beverages, and more). DiNP metabolites were associated with intake of meat and grains.1
The authors also found that the associations between phthalates and fast food were not uniform across the population.1 They speculate that the pronounced association they saw between fast food consumption and DEHP in black consumers could reflect higher overall consumption of fast food and/or different food choices among this population. Prior research suggests that predominately black neighborhoods in urban areas have a greater density of fast food restaurants than white neighborhoods.3
“The fact that non-Hispanic blacks showed a steeper dose–response curve to fast food and DEHP is an important contribution to the environmental justice field since it suggests a potential connection between neighborhood environments, food choices, and phthalates exposure,” says lead author Ami Zota, an assistant professor of environmental and occupational health at George Washington University. Environmental justice research has found that minority populations often have greater environmental exposures to potentially harmful agents than other groups.4
The authors point to PVC tubing, vinyl gloves used for food handling, and food packaging as possible sources of phthalate contamination in fast food. DEHP is a ubiquitous high-molecular-weight phthalate that has been removed from some products due to concerns about potential adverse health effects.5 In some cases it is being replaced with DiNP.2
The study measured only exposures, not the potential health effects of fast food itself or of exposure to phthalates in fast food. At the same time, says Ruthann Rudel, director of research at the Silent Spring Institute, “One important implication of this finding is that dietary habits such as fast food intake may confound associations between urinary phthalate metabolite levels and health effects in epidemiology studies.” Rudel was not involved in the study.
“Dr. Zota has leveraged available resources from a nationally representative study population in a very savvy way to answer an interesting research question about chemical exposure via food packaging and processing,” says Megan Romano, a postdoctoral research associate in epidemiology at Brown University, who was not involved with the research. “The next steps are to better describe which types of foods have high levels of phthalate contamination and to identify the source of the phthalate contamination, be it processing or contact with food packaging.”
1. Zota AR, et al. Recent fast food consumption and bisphenol A and phthalates exposures among the U.S. population in NHANES, 2003–2010. Environ Health Perspect 124(10):1521–1528 (2016), doi: 10.1289/ehp.1510803.
2. CDC. National Health and Nutrition Examination Survey. 2003–2004 Data Documentation, Codebook, and Frequencies. Dietary Interview–Individual Foods, First Day (DR1IFF_C). Available: http://wwwn.cdc.gov/nchs/nhanes/2003-2004/DR1IFF_C.htm [accessed 13 June 2016].
3. Powell Lisa M, et al. The availability of fast-food and full-service restaurants in the United States: associations with neighborhood characteristics. Am J Prev Med 33(suppl 4):S240–S245 (2007), doi: 10.1016/j.amepre.2007.07.005.
4. Ringquist EJ. Assessing evidence of environmental inequities: a meta-analysis. J Policy Anal Manage 24(2):223–247 (2005), doi: 10.1002/pam.20088.
5. Zota AR, et al. Temporal trends in phthalate exposures: findings from the National Health and Nutrition Examination Survey, 2001–2010. Environ Health Perspect 122(3):235–241 (2014), doi: 10.1289/ehp.1306681.
This month EHP’s Children’s Health section highlights recent laboratory research about health effects of early-life exposures. By showing causative linkage between specific exposures and various health outcomes in animal models, toxicologists help to confirm associations found in observational human studies. Together, toxicologists and epidemiologists build the scientific evidence base used by risk assessors and regulators to protect children’s health.
Learn more about rigor and transparency in scientific publishing at the 2017 SOT Annual Meeting and ToxExpo, as EHP Editor-in-Chief Sally Perreault Darney chairs and speaks at an Informational Session titled “Addressing Rigor and Transparency in Research and Journal Publication.” At the session, scheduled for Wednesday, March 15, at 5:00 PM in Room CC 314, Sally will talk about interdisciplinary challenges for rigor and reproducibility in environmental health research. More details are available in the SOT 2017 Conference Program.
EHP is pleased to announce that “Reducing Phthalate, Paraben, and Phenol Exposure from Personal Care Products in Adolescent Girls: Findings from the HERMOSA Intervention Study,” published in EHP on 7 March 2016, has been selected by the Children’s Environmental Health Network (CEHN) as its March 2017 Article of the Month. CEHN Article of the Month summaries discuss the potential policy implications of current children’s environmental health research. The CEHN summary can be viewed here.