April 2013 | Volume 121 | Issue 4
Lyme disease is the most common vectorborne infection in North America, and the ecology of the causative agent, a spirochete named Borrelia burgdorferi, is the subject of both intense study and intense scientific debate. Some researchers think protecting large tracts of forest habitat will ultimately reduce the risk of human infection. Others believe the relationship between host biodiversity and human disease risk is not so clearcut.
Spheres of Influence
The Federal Food, Drug, and Cosmetic (FD&C) Act of 1938 has been amended over the years in attempts to streamline and bring order to the sprawling task of assessing and categorizing the thousands of substances used in foods, drugs, and cosmetics. One result of this streamlining is that under current U.S. law, companies can add certain types of ingredients to foods without premarket approval from the Food and Drug Administration (FDA). Is this a problem? The answer depends on whom you ask.
Unclear Relationship: Prenatal but Not Concurrent Bisphenol A Exposure Linked to Lower Weight and Less Fat
Toward Primary Prevention of Cancer: The Case for a Global Strategy to Limit Environmental and Occupational Exposures
Climate Change, Human Health, and Biomedical Research: Analysis of the National Institutes of Health Research Portfolio
Environmental and Occupational Interventions for Primary Prevention of Cancer: A Cross-Sectorial Policy Framework
Arsenic Exposure from Drinking Water and QT-Interval Prolongation: Results from the Health Effects of Arsenic Longitudinal Study
The Natural Estrogenic Compound Diarylheptanoid (D3): In Vitro Mechanisms of Action and in Vivo Uterine Responses via Estrogen Receptor α
Biotransformation of BDE‑47 to Potentially Toxic Metabolites Is Predominantly Mediated by Human CYP2B6
Association of Osteoarthritis with Perfluorooctanoate and Perfluorooctane Sulfonate in NHANES 2003–2008
Associations of in Utero Exposure to Perfluorinated Alkyl Acids with Human Semen Quality and Reproductive Hormones in Adult Men
Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes
Polymorphisms in Iron Homeostasis Genes and Urinary Cadmium Concentrations among Nonsmoking Women in Argentina and Bangladesh
Performance in Omics Analyses of Blood Samples in Long-Term Storage: Opportunities for the Exploitation of Existing Biobanks in Environmental Health Research
Gestational Diabetes and Preeclampsia in Association with Air Pollution at Levels below Current Air Quality Guidelines
Urban Tree Canopy and Asthma, Wheeze, Rhinitis, and Allergic Sensitization to Tree Pollen in a New York City Birth Cohort
Race/Ethnicity–Specific Associations of Urinary Phthalates with Childhood Body Mass in a Nationally Representative Sample
Serum Polyfluoroalkyl Concentrations, Asthma Outcomes, and Immunological Markers in a Case–Control Study of Taiwanese Children
Maria Neira, R. Thomas Zoeller, Georg Becher, Poul Bjerregaard, Riana Bornman, Ingvar Brandt,
Andreas Kortenkamp, Derek Muir, Marie-Noël Brune Drisse, Roseline Ochieng, Niels E. Skakkebaek,
Agneta Sundén Byléhn, Taisen Iguchi, Jorma Toppari, and Tracey J. Woodruff | A104
Erratum: Perfluorooctanoic Acid Concentrations for Participants in the C8 Health Project [119(12):1760–1765 (2011)]
Erratum: Braun et al. “Variability of Urinary Phthalate Metabolite and Bisphenol A Concentrations before and during Pregnancy” [120:739–745 (2012)]
This month EHP’s Children’s Health section highlights recent laboratory research about health effects of early-life exposures. By showing causative linkage between specific exposures and various health outcomes in animal models, toxicologists help to confirm associations found in observational human studies. Together, toxicologists and epidemiologists build the scientific evidence base used by risk assessors and regulators to protect children’s health.
Learn more about rigor and transparency in scientific publishing at the 2017 SOT Annual Meeting and ToxExpo, as EHP Editor-in-Chief Sally Perreault Darney chairs and speaks at an Informational Session titled “Addressing Rigor and Transparency in Research and Journal Publication.” At the session, scheduled for Wednesday, March 15, at 5:00 PM in Room CC 314, Sally will talk about interdisciplinary challenges for rigor and reproducibility in environmental health research. More details are available in the SOT 2017 Conference Program.