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Children’s Health Collection 2015

The Children’s Health Collection comprises peer-reviewed research articles, reviews, commentaries, editorials, news, and Science Selections published in EHP from October 2014 through September 2015 (

  • CH Collection Cover 2015Children’s Health Collection 2015 comprises abstracts of all relevant articles published in EHP from October 2014 through September 2015: peer-reviewed research articles, news features, Science Selections, and editorials. Abstracts are featured for each research article published in an issue, and hyperlinks take readers directly to the full article online ( The Science Selections are noted just below the related research.

    As in previous Collections, the three main sections—Disease Outcomes, Exposures, and Methodologies and Populations—contain all research that has appeared in the Children’s Health section of each EHP issue as well as relevant reviews and commentaries, research that involves both adult and child cohorts and both animal and human components, diseases with fetal or childhood origins, experimental models with direct application to children’s health and pediatric practice, and topics of general interest to children’s health researchers and advocates. Some specific topics (e.g., Food Safety, Insecurity, Nutrition) are featured in news articles but not in research.

    New this year is the inclusion of Advance Publication articles—articles that have been accepted, but not yet copyedited and added to a specific issue—published online through September. These appear at the end of each topic area; each includes the doi information but not an abstract. The doi link will access the most recent form of the article, whether Advance Publication or the copyedited final version.

    As developing topics, analyses of green (and blue) space show how these physical spaces provide benefits in, for example, birth weight and neurodevelopment as well as reductions in obesity; and analyses of multiple exposures reflect the complexity of interactions and outcomes. New categories are Natural Gas and Fracking, demonstrating this technique’s potential health impacts and environmental damage, and Global Health. Besides the many articles in other sections that analyze data from around the world, Global Health includes an extensive review of various exposures throughout Latin America as well as efforts to address them, and a study of biomonitoring throughout Europe. In addition, studies that combine multiple cohorts (e.g., ESCAPE, NewGeneris), databases, methodologies, and analyses of multiple environmental factors and outcomes reflect efforts to harmonize data and address the variety of exposures and outcomes around the world. The Navigation Guide systematic reviews provide methods for synthesizing these data, and articles on climate change reflect trends that have global impact.

    Please see for all the yearly Children’s Health collections. This collection is also available as a 6MB PDF.

    Martha M. Dimes, PhD
    Children’s Health Editor

  • Asthma/Respiratory Disease, Lung Development, Allergy open

    Perfluoroalkyl Chemicals and Asthma among Children 12–19 Years of Age: NHANES (1999–2008)

    Olivier Humblet, Ledif Grisell Diaz-Ramirez, John R. Balmes, Susan M. Pinney, and Robert A. Hiatt

    Asthma in Inner-City Children at 5–11 Years of Age and Prenatal Exposure to Phthalates: The Columbia Center for Children’s Environmental Health Cohort

    Robin M. Whyatt, Matthew S. Perzanowski, Allan C. Just, Andrew G. Rundle, Kathleen M. Donohue, Antonia M. Calafat, Lori A. Hoepner, Frederica P. Perera, and Rachel L. Miller

    Indoor Environmental Exposures and Exacerbation of Asthma: An Update to the 2000 Review by the Institute of Medicine

    Watcharoot Kanchongkittiphon, Mark J. Mendell, Jonathan M. Gaffin, Grace Wang, and Wanda Phipatanakul

    Early-life Exposure to Organophosphate Pesticides and Pediatric Respiratory Symptoms in the CHAMACOS Cohort

    Rachel Raanan, Kim G. Harley, John R. Balmes, Asa Bradman, Michael Lipsett, and Brenda Eskenazi

    Perinatal Exposure to Traffic-Related Air Pollution and Atopy at 1 Year of Age in a Multi-Center Canadian Birth Cohort Study

    Hind Sbihi, Ryan W. Allen, Allan Becker, Jeffrey R. Brook, Piush Mandhane, James A. Scott, Malcolm R. Sears, Padmaja Subbarao, Tim K. Takaro, Stuart E. Turvey, and Michael Brauer

    ADVANCE PUBLICATION | Urinary Dialkyl Phosphate Concentrations and Lung Function Parameters in Adolescents and Adults: Results from the Canadian Health Measures Survey

    Ming Ye, Jeremy Beach, Jonathan W. Martin, and Ambikaipakan Senthilselvan

    Neurodevelopment, Neurobehavior, Intelligence Assessment open

    Environmental Tobacco Smoke Exposure and Children’s Intelligence at 8–11 Years of Age

    Subin Park, Soo-Churl Cho, Yun-Chul Hong, Jae-Won Kim, Min-Sup Shin, Hee Jeong Yoo, Doug Hyun Han, Jae Hoon Cheong, and Bung-Nyun Kim

    Pyrethroid Pesticide Exposure and Parental Report of Learning Disability and Attention Deficit/Hyperactivity Disorder in U.S. Children: NHANES 1999–2002

    Lesliam Quirós-Alcalá, Suril Mehta, and Brenda Eskenazi

    Neurobehavioral Function in School-Age Children Exposed to Manganese in Drinking Water

    Youssef Oulhote, Donna Mergler, Benoit Barbeau, David C. Bellinger, Thérèse Bouffard, Marie-Ève Brodeur, Dave Saint-Amour, Melissa Legrand, Sébastien Sauvé, and Maryse F. Bouchard

    Prenatal Organochlorine and Methylmercury Exposure and Memory and Learning in School-Age Children in Communities Near the New Bedford Harbor Superfund Site, Massachusetts

    Sara T.C. Orenstein, Sally W. Thurston, David C. Bellinger, Joel D. Schwartz, Chitra J. Amarasiriwardena, Larisa M. Altshul, and Susan A. Korrick

    Prenatal Exposure to Phthalate Esters and Behavioral Syndromes in Children at 8 Years of Age: Taiwan Maternal and Infant Cohort Study

    Yin-Ju Lien, Hsiu-Ying Ku, Pen-Hua Su, Suh-Jen Chen, Hsiao-Yen Chen, Pao-Chi Liao, Wei-J. Chen, and Shu-Li Wang

    Environmental Lead Exposure and Attention Deficit/Hyperactivity Disorder Symptom Domains in a Community Sample of South Korean School-Age Children

    Soon-Beom Hong, Mee-Hyang Im, Jae-Won Kim, Eun-Jin Park, Min-Sup Shin, Boong-Nyun Kim, Hee-Jeong Yoo, In-Hee Cho, Soo-Young Bhang, Yun-Chul Hong, and Soo-Churl Cho

    Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort

    Zeyan Liew, Beate Ritz, Ondine S. von Ehrenstein, Bodil Hammer Bech, Ellen Aagaard Nohr, Chunyuan Fei, Rossana Bossi, Tine Brink Henriksen, Eva Cecilie Bonefeld-Jørgensen, and Jørn Olsen

    Maternal Blood Manganese and Early Neurodevelopment: The Mothers and Children’s Environmental Health (MOCEH) Study

    Soo Eun Chung, Hae-Kwan Cheong, Eun-Hee Ha, Boong-Nyun Kim, Mina Ha, Yangho Kim, Yun-Chul Hong, Hyesook Park, and Se-Young Oh

    Relation of Prenatal Methylmercury Exposure from Environmental Sources to Childhood IQ

    Joseph L. Jacobson, Gina Muckle, Pierre Ayotte, Éric Dewailly, and Sandra W. Jacobson

    Measured Prenatal and Estimated Postnatal Levels of Polychlorinated Biphenyls (PCBs) and ADHD-Related Behaviors in 8-Year-Old Children

    Marc-André Verner, Jaime E. Hart, Sharon K. Sagiv, David C. Bellinger, Larisa M. Altshul, and Susan A. Korrick

    ADVANCE PUBLICATION | Exposure to Road Traffic Noise and Behavioral Problems in 7-Year-Old Children: A Cohort Study

    Dorrit Hjortebjerg, Anne Marie Nybo Andersen, Jeppe Schultz Christensen, Matthias Ketzel, Ole Raaschou-Nielsen, Jordi Sunyer, Jordi Julvez, Joan Forns, and Mette Sørensen

    ADVANCE PUBLICATION | Traffic-Related Air Pollution, Noise at School, and Behavioral Problems in Barcelona Schoolchildren: A Cross-Sectional Study

    Joan Forns, Payam Dadvand, Maria Foraster, Mar Alvarez-Pedrerol, Ioar Rivas, Mònica López-Vicente, Elisabet Suades-Gonzalez, Raquel Garcia-Esteban, Mikel Esnaola, Marta Cirach, James Grellier, Xavier Basagaña, Xavier Querol, Mònica Guxens, Mark J. Nieuwenhuijsen, and Jordi Sunyer

    ADVANCE PUBLICATION | Prenatal Organophosphorus Pesticide Exposure and Child Neurodevelopment at 24 Months: An Analysis of Four Birth Cohorts

    Stephanie M. Engel, Asa Bradman, Mary S. Wolff, Virginia A. Rauh, Kim G. Harley, Jenny H. Yang, Lori A. Hoepner, Dana Boyd Barr, Kimberly Yolton, Michelle G. Vedar, Yingying Xu, Richard W. Hornung, James G. Wetmur, Jia Chen, Nina T. Holland, Frederica P. Perera, Robin M. Whyatt, Bruce P. Lanphear, and Brenda Eskenazi

    ADVANCE PUBLICATION | Organophosphate Insecticide Metabolites in Prenatal and Childhood Urine Samples and Intelligence Scores at 6 Years of Age: Results from the Mother–Child PELAGIE Cohort (France)

    Chloé Cartier, Charline Warembourg, Gaïd Le Maner-Idrissi, Agnès Lacroix, Florence Rouget, Christine Monfort, Gwendolina Limon, Gaël Durand, Dave Saint-Amour, Sylvaine Cordier, and Cécile Chevrier

    Autism open

    Neurodevelopmental Disorders and Prenatal Residential Proximity to Agricultural Pesticides: The CHARGE Study

    Janie F. Shelton, Estella M. Geraghty, Daniel J. Tancredi, Lora D. Delwiche, Rebecca J. Schmidt, Beate Ritz, Robin L. Hansen, and Irva Hertz-Picciotto

    Autism Spectrum Disorder and Particulate Matter Air Pollution before, during, and after Pregnancy: A Nested Case–Control Analysis within the Nurses’ Health Study II Cohort

    Raanan Raz, Andrea L. Roberts, Kristen Lyall, Jaime E. Hart, Allan C. Just, Francine Laden, and Marc G. Weisskopf

    ADVANCE PUBLICATION | Air Pollution Exposure during Pregnancy and Childhood Autistic Traits in Four European Population-Based Cohort Studies: The ESCAPE Project

    Mònica Guxens, Akhgar Ghassabian, Tong Gong, Raquel Garcia-Esteban, Daniela Porta, Lise Giorgis-Allemand, Catarina Almqvist, Aritz Aranbarri, Rob Beelen, Chiara Badaloni, Giulia Cesaroni, Audrey de Nazelle, Marisa Estarlich, Francesco Forastiere, Joan Forns, Ulrike Gehring, Jesús Ibarluzea, Vincent W.V. Jaddoe, Michal Korek, Paul Lichtenstein, Mark J. Nieuwenhuijsen, Marisa Rebagliato, Rémy Slama, Henning Tiemeier, Frank C. Verhulst, Heather E. Volk, Göran Pershagen, Bert Brunekreef, and Jordi Sunyer

    Cancers open

    Residential Levels of Polybrominated Diphenyl Ethers and Risk of Childhood Acute Lymphoblastic Leukemia in California

    Mary H. Ward, Joanne S. Colt, Nicole C. Deziel, Todd P. Whitehead, Peggy Reynolds, Robert B. Gunier, Marcia Nishioka, Gary V. Dahl, Stephen M. Rappaport, Patricia A. Buffler, and Catherine Metayer

    Birth Defects open

    Prenatal Phthalate Exposures and Anogenital Distance in Swedish Boys

    Carl-Gustaf Bornehag, Fredrik Carlstedt, Bo AG. Jönsson, Christian H. Lindh, Tina K. Jensen, Anna Bodin, Carin Jonsson, Staffan Janson, and Shanna H. Swan

    ADVANCE PUBLICATION | Perfluorooctane Sulfonate Concentrations in Amniotic Fluid, Biomarkers of Fetal Leydig Cell Function, and Cryptorchidism and Hypospadias in Danish Boys (1980-1996)

    Gunnar Toft, Bo A.G. Jönsson, Jens Peter Bonde, Bent Nørgaard-Pedersen, David M. Hougaard, Arieh Cohen, Christian H. Lindh, Richard Ivell, Ravinder Anand-Ivell, and Morten S. Lindhard

    ADVANCE PUBLICATION | Organic Food Consumption during Pregnancy and Hypospadias and Cryptorchidism at Birth: The Norwegian Mother and Child Cohort Study (MoBa)

    Anne Lise Brantsæter, Hanne Torjusen, Helle Margrete Meltzer, Eleni Papadopoulou, Jane A. Hoppin, Jan Alexander, Geir Lieblein, Gun Roos, Jon Magne Holten, Jackie Swartz, and Margaretha Haugen

    Eyes and Ears open

    Prenatal and Postnatal Serum PCB Concentrations and Cochlear Function in Children at 45 Months of Age

    Todd A. Jusko, Renata Sisto, Ana-Maria Iosif, Arturo Moleti, Soňa Wimmerová, Kinga Lancz, Juraj Tihányi, Eva Šovčíková, Beata Drobná, L’ubica Palkovičová, Dana Jurečková, Kelly Thevenet-Morrison, Marc-André Verner, Dean Sonneborn, Irva Hertz-Picciotto, and Tomáš Trnovec

    Pregnancy Outcomes: Preterm Birth, Small for Gestational Age, Fetal Development, Pregnancy Loss open

    Preconception Maternal and Paternal Exposure to Persistent Organic Pollutants and Birth Size: The LIFE Study

    Candace A. Robledo, Edwina Yeung, Pauline Mendola, Rajeshwari Sundaram, Jose Maisog, Anne M. Sweeney, Dana Boyd Barr, and Germaine M. Buck Louis

    Paternal Urinary Concentrations of Parabens and Other Phenols in Relation to Reproductive Outcomes among Couples from a Fertility Clinic

    Laura E. Dodge, Paige L. Williams, Michelle A. Williams, Stacey A. Missmer, Thomas L. Toth, Antonia M. Calafat, and Russ Hauser

    Urinary Bisphenol A Levels during Pregnancy and Risk of Preterm Birth

    David E. Cantonwine, Kelly K. Ferguson, Bhramar Mukherjee, Thomas F. McElrath, and John D. Meeker

    ADVANCE PUBLICATION | Geographic Variation in the Association between Ambient Fine Particulate Matter (PM2.5) and Term Low Birth Weight in the United States

    Yongping Hao, Heather Strosnider, Lina Balluz, and Judith R. Qualters

    ADVANCE PUBLICATION | Associations of Pregnancy Outcomes and PM2.5 in a National Canadian Study

    David M. Stieb, Li Chen, Bernardo S. Beckerman, Michael Jerrett, Daniel L. Crouse, D. Walter Rasugu Omariba, Paul A. Peters, Aaron van Donkelaar, Randall V. Martin, Richard T. Burnett, Nicolas L. Gilbert, Michael Tjepkema, Shiliang Liu, and Rose M. Dugandzic

    ADVANCE PUBLICATION | Prenatal Exposure to NO2 and Ultrasound Measures of Fetal Growth in the Spanish INMA Cohort

    Carmen Iñiguez, Ana Esplugues, Jordi Sunyer, Mikel Basterrechea, Ana Fernández-Somoano, Olga Costa, Marisa Estarlich, Inmaculada Aguilera, Aitana Lertxundi, Adonina Tardón, Mònica Guxens, Mario Murcia, Maria-Jose Lopez-Espinosa, and Ferran Ballester, on behalf of the INMA Project

    ADVANCE PUBLICATION | Cord Blood Methylmercury and Fetal Growth Outcomes in Baltimore Newborns: Potential Confounding and Effect Modification by Omega-3 Fatty Acids, Selenium, and Sex

    Ellen M. Wells, Julie B. Herbstman, Yu Hong Lin, Jeffery Jarrett, Carl P. Verdon, Cynthia Ward, Kathleen L. Caldwell, Joseph R. Hibbeln, Frank R. Witter, Rolf U. Halden, and Lynn R. Goldman

    ADVANCE PUBLICATION | Exposure to Bisphenol A and Phthalates during Pregnancy and Ultrasound Measures of Fetal Growth in the INMA-Sabadell Cohort

    Maribel Casas, Damaskini Valvi, Ana Ballesteros-Gomez, Mireia Gascon, Mariana F. Fernández, Raquel Garcia-Esteban, Carmen Iñiguez, David Martínez, Mario Murcia, Nuria Monfort, Noelia Luque, Soledad Rubio, Rosa Ventura, Jordi Sunyer, and Martine Vrijheid

    ADVANCE PUBLICATION | Urinary Concentrations of Phthalate Metabolites and Bisphenol A and Associations with Follicular-Phase Length, Luteal-Phase Length, Fecundability, and Early Pregnancy Loss

    Anne Marie Jukic, Antonia M. Calafat, D. Robert McConnaughey, Matthew P. Longnecker, Jane A. Hoppin, Clarice R. Weinberg, Allen J. Wilcox, and Donna D. Baird

    ADVANCE PUBLICATION | Blood Biomarkers of Late Pregnancy Exposure to Trihalomethanes in Drinking Water and Fetal Growth Measures and Gestational Age in a Chinese Cohort

    Wen-Cheng Cao, Qiang Zeng, Yan Luo, Hai-Xia Chen, Dong-Yue Miao, Li Li, Ying-Hui Cheng, Min Li, Fan Wang, Ling You, Yi-Xin Wang, Pan Yang, and Wen-Qing Lu

    ADVANCE PUBLICATION | Prenatal Ambient Air Pollution, Placental Mitochondrial DNA Content, and Birth Weight in the INMA (Spain) and ENVIRONAGE (Belgium) Birth Cohorts

    Diana B.P. Clemente, Maribel Casas, Nadia Vilahur, Haizea Begiristain, Mariona Bustamante, Anne-Elie Carsin, Mariana F. Fernández, Frans Fierens, Wilfried Gyselaers, Carmen Iñiguez, Bram G. Janssen, Wouter Lefebvre, Sabrina Llop, Nicolás Olea, Marie Pedersen, Nicky Pieters, Loreto Santa Marina, Ana Souto, Adonina Tardón, Charlotte Vanpoucke, Martine Vrijheid, Jordi Sunyer, and Tim S. Nawrot

    Infections open

    FOCUS | The WASH Approach: Fighting Waterborne Diseases in Emergency Situations

    Wendee Nicole

    Refugees with 20-liter jerrycans
    Emergency situations are prime settings for outbreaks of diseases spread by fecal–oral transmission. In times of scarcity, water tends to go first to drinking and cooking, while hygiene often gets short shrift. Having adequate water is not enough, however; health-protective behaviors are critically important for preventing the spread of waterborne diseases.
    © Wendee Nicole

    ADVANCE PUBLICATION | Infant Infections and Respiratory Symptoms in Relation to in Utero Arsenic Exposure in a U.S. Cohort

    Shohreh F. Farzan, Zhigang Li, Susan A. Korrick, Donna Spiegelman, Richard Enelow, Kari Nadeau, Emily Baker, and Margaret R. Karagas

    Fetal or Early-life Exposures Contributing to Later Childhood or Adult Disease open

    BRIEF COMMUNICATION | Current Research and Opportunities to Address Environmental Asbestos Exposures

    Danielle J. Carlin, Theodore C. Larson, Jean C. Pfau, Stephen H. Gavett, Arti Shukla, Aubrey Miller, and Ronald Hines

    ADVANCE PUBLICATION | Prenatal Exposure to Perfluoroalkyl Acids and Serum Testosterone Concentrations at 15 Years of Age in Female ALSPAC Study Participants

    Mildred Maisonet, Antonia M. Calafat, Michele Marcus, Jouni J.K. Jaakkola, and Hany Lashen

    ADVANCE PUBLICATION | Mechanisms Underlying Latent Disease Risk Associated with Early-Life Arsenic Exposure: Current Research Trends and Scientific Gaps

    Kathryn A. Bailey, Allan H. Smith, Erik J. Tokar, Joseph H. Graziano, Kyoung-Woong Kim, Panida Navasumrit, Mathuros Ruchirawat, Apinya Thiantanawat, William A. Suk, and Rebecca C. Fry

    ADVANCE PUBLICATION | Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood

    Yue Li, Changchun Xie, Susan K. Murphy, David Skaar, Monica Nye, Adriana C. Vidal, Kim M. Cecil, Kim N. Dietrich, Alvaro Puga, Randy L. Jirtle, and Cathrine Hoyo

    Infant and Childhood Growth and Obesity open

    A Longitudinal Cohort Study of Body Mass Index and Childhood Exposure to Secondhand Tobacco Smoke and Air Pollution: The Southern California Children’s Health Study

    Rob McConnell, Ernest Shen, Frank D. Gilliland, Michael Jerrett, Jennifer Wolch, Chih-Chieh Chang, Frederick Lurmann, and Kiros Berhane

    Prenatal and Postnatal Exposure to Persistent Organic Pollutants and Infant Growth: A Pooled Analysis of Seven European Birth Cohorts

    Nina Iszatt, Hein Stigum, Marc-André Verner, Richard A. White, Eva Govarts, Lubica Palkovicova Murinova, Greet Schoeters, Tomas Trnovec, Juliette Legler, Fabienne Pelé, Jérémie Botton, Cécile Chevrier, Jürgen Wittsiepe, Ulrich Ranft, Stéphanie Vandentorren, Monika Kasper-Sonnenberg, Claudia Klümper, Nynke Weisglas-Kuperus, Anuschka Polder, Merete Eggesbø, and OBELIX

    ADVANCE PUBLICATION | Thyroid Antagonists (Perchlorate, Thiocyanate, and Nitrate) and Childhood Growth in a Longitudinal Study of U.S. Girls

    Nancy A. Mervish, Ashley Pajak, Susan L. Teitelbaum, Susan M. Pinney, Gayle C. Windham, Lawrence H. Kushi, Frank M. Biro, Liza Valentin-Blasini, Benjamin C. Blount, and Mary S. Wolff, for the Breast Cancer and Environment Research Project (BCERP)

    ADVANCE PUBLICATION | Prenatal Phthalate Exposures and Childhood Fat Mass in a New York City Cohort

    Jessie P. Buckley, Stephanie M. Engel, Michelle A. Mendez, David B. Richardson, Julie L. Daniels, Antonia M. Calafat, Mary S. Wolff, and Amy H. Herring

    Diabetes open

    Association between Ambient Air Pollution and Diabetes Mellitus in Europe and North America: Systematic Review and Meta-Analysis

    Ikenna C. Eze, Lars G. Hemkens, Heiner C. Bucher, Barbara Hoffmann, Christian Schindler, Nino Künzli, Tamara Schikowski, and Nicole M. Probst-Hensch

    Food Safety, Insecurity, Nutrition open

    FOCUS | Beyond Malnutrition: The Role of Sanitation in Stunted Growth

    Charles W. Schmidt

    Three Indian children
    Worldwide, stunted growth affects an estimated 165 million children under age 5. Reducing stunting is a global priority for international health organizations and donors, but it’s clear that nutritional interventions alone won’t get the job done. That’s because stunting isn’t just a nutritional problem; it’s also an environmental one.
    © Roger Parkes/Alamy

    FOCUS | Pollinator Power: Nutrition Security Benefits of an Ecosystem Service

    Wendee Nicole

    Scientists have only recently calculated the extent to which food supplies depend on pollinators. Now several new studies suggest that reduced populations of bees and other pollinators may adversely affect not only the marketplace but also the availability of essential nutrients in the human diet, potentially increasing malnutrition in areas already struggling with this issue.

  • Heavy Metals (e.g., lead, mercury) open

    SPHERES OF INFLUENCE | In Search of “Just Right”: The Challenge of Regulating Arsenic in Rice

    Charles W. Schmidt

    White and brown rice
    Many countries regulate arsenic in municipal water. Now research and regulatory concerns are broadening to include arsenic in the diet, especially in rice, but settling on an appropriate limit for arsenic in rice is proving difficult.
    © 145/Steve Outram/Ocean/Corbis

    Blood Lead Concentration and Thyroid Function during Pregnancy: Results from the Yugoslavia Prospective Study of Environmental Lead Exposure

    Linda G. Kahn, Xinhua Liu, Biljana Rajovic, Dusan Popovac, Sharon Oberfield, Joseph H. Graziano, and Pam Factor-Litvak

    Association of Arsenic and Metals with Concentrations of 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D among Adolescents in Torreón, Mexico

    Rachel D. Zamoiski, Eliseo Guallar, Gonzalo G. García-Vargas, Stephen J. Rothenberg, Carol Resnick, Marisela Rubio Andrade, Amy J. Steuerwald, Patrick J. Parsons, Virginia M. Weaver, Ana Navas-Acien, and Ellen K. Silbergeld

    Association of Arsenic with Adverse Pregnancy Outcomes/Infant Mortality: A Systematic Review and Meta-Analysis

    Reginald Quansah, Frederick Ato Armah, David Kofi Essumang, Isaac Luginaah, Edith Clarke, Kissinger Marfoh, Samuel Jerry Cobbina, Edward Nketiah-Amponsah, Proscovia Bazanya Namujju, Samuel Obiri, and Mawuli Dzodzomenyo

    Estimated Exposure to Arsenic in Breastfed and Formula-Fed Infants in a United States Cohort

    Courtney C. Carignan, Kathryn L. Cottingham, Brian P. Jackson, Shohreh F. Farzan, A. Jay Gandolfi, Tracy Punshon, Carol L. Folt, and Margaret R. Karagas

    Arsenic Exposure and Prevalence of the Varicella Zoster Virus in the United States: NHANES (2003–2004 and 2009–2010)

    Andres Cardenas, Ellen Smit, E. Andres Houseman, Nancy I. Kerkvliet, Jeffrey W. Bethel, and Molly L. Kile

    Blood Pressure, Left Ventricular Geometry, and Systolic Function in Children Exposed to Inorganic Arsenic

    Citlalli Osorio-Yáñez, Julio C. Ayllon-Vergara, Laura Arreola-Mendoza, Guadalupe Aguilar-Madrid, Erika Hernández-Castellanos, Luz C. Sánchez-Peña, and Luz M. Del Razo

    Mercury Exposure and Antinuclear Antibodies among Females of Reproductive Age in the United States: NHANES

    Emily C. Somers, Martha A. Ganser, Jeffrey S. Warren, Niladri Basu, Lu Wang, Suzanna M. Zick, and Sung Kyun Park

    ADVANCE PUBLICATION | Evaluation of an Elementary School–based Educational Intervention for Reducing Arsenic Exposure in Bangladesh

    Khalid Khan, Ershad Ahmed, Pam Factor-Litvak, Xinhua Liu, Abu B. Siddique, Gail A. Wasserman, Vesna Slavkovich, Diane Levy, Jacob L. Mey, Alexander van Geen, and Joseph H. Graziano

    ADVANCE PUBLICATION | A Case–Control Study of Prenatal Thallium Exposure and Low Birth Weight in China

    Wei Xia, Xiaofu Du, Bin Zhang, Yuanyuan Li, Bryan A. Bassig, Aifen Zhou, Youjie Wang, Chao Xiong, Zhengkuan Li, Yuanxiang Yao, Jie Hu, Yanqiu Zhou, Qi Wang, Juan Liu, Weiyan Xue, Yue Ma, Xinyun Pan, Yang Peng, Tongzhang Zheng, and Shunqing Xu

    ADVANCE PUBLICATION | Confusion about Cadmium Risks: The Unrecognized Limitations of an Extrapolated Paradigm

    Alfred Bernard

    ADVANCE PUBLICATION | Use of a Cumulative Exposure Index to Estimate the Impact of Tap-Water Lead Concentration on Blood Lead Levels in 1- to 5-Year-Old Children (Montreal, Canada)

    Gerard Ngueta, Belkacem Abdous, Robert Tardif, Julie St-Laurent, and Patrick Levallois

    Pesticides and Other Chemicals/Compounds (e.g., BPA, PCBs, PBDEs, PFCs, phthalates, endocrine disruptors) open

    FOCUS | Hand-Me-Down Hazard: Flame Retardants in Discarded Foam Products

    Kellyn S. Betts

    Furniture industry experts expect flame-retardant-free furnishings to become increasingly popular with consumers who can afford them, and people who purchase these items may reduce their exposures to certain flame retardants. But what happens to older furniture that enters the waste stream?

    FOCUS | More than Cosmetic Changes: Taking Stock of Personal Care Product Safety

    Rebecca Kessler

    Prototypes of reformulated baby care products
    In recent years, under mounting pressure from advocacy groups, a number of major manufacturers and retailers have begun eliminating controversial ingredients from the personal care products they produce and sell. Companies are investing considerable resources to reformulate their products, even as they universally defend the questioned ingredients.
    © Rebecca Kessler

    SPHERES OF INFLUENCE | Chemical Footprinting: Identifying Hidden Liabilities in Manufacturing Consumer Products

    Lindsey Konkel

    Corporate chemicals management policies have traditionally revolved around making sure certain chemicals aren’t found in products over a mandated threshold. Manufacturers are now going a step farther, using “chemical footprinting” to identify and manage hidden chemical liabilities in products and supply chains.

    EDITORIAL | Alternatives to PFASs: Perspectives
    on the Science

    Linda S. Birnbaum and Philippe Grandjean

    BRIEF COMMUNICATION | The Madrid Statement on
    Poly- and Perfluoroalkyl Substances (PFASs)

    Arlene Blum, Simona A. Balan, Martin Scheringer, Xenia Trier, Gretta Goldenman, Ian T. Cousins, Miriam Diamond, Tony Fletcher, Christopher Higgins, Avery E. Lindeman, Graham Peaslee, Pim de Voogt, Zhanyun Wang, and Roland Weber

    BRIEF COMMUNICATION | Fluorotechnology Is Critical to Modern Life: The FluoroCouncil Counterpoint to the Madrid Statement

    Jessica S. Bowman

    FOCUS | A Hard Nut to Crack: Reducing Chemical Migration in Food-Contact Materials

    Nate Seltenrich

    Figure showing various types of food packaging
    Although food packaging serves important safety functions, these painstakingly engineered containers can also leach chemicals and other contaminants into the food and drink they protect. Researchers and food producers are searching for ways to stem this chemical migration, but solutions are proving elusive.
    © Roy Scott

    Early-Life Bisphenol A Exposure and Child Body Mass Index: A Prospective Cohort Study

    Joseph M. Braun, Bruce P. Lanphear, Antonia M. Calafat, Sirad Deria, Jane Khoury, Chanelle J. Howe, and Scott A. Venners

    Aerial Application of Mancozeb and Urinary Ethylene Thiourea (ETU) Concentrations among Pregnant Women in Costa Rica: The Infants’ Environmental Health Study (ISA)

    Berna van Wendel de Joode, Ana María Mora, Leonel Córdoba, Juan Camilo Cano, Rosario Quesada, Moosa Faniband, Catharina Wesseling, Clemens Ruepert, Mattias Öberg, Brenda Eskenazi, Donna Mergler, and Christian H. Lindh

    Evaluating Health Risks from Inhaled Polychlorinated Biphenyls: Research Needs for Addressing Uncertainty

    Geniece M. Lehmann, Krista Christensen, Mark Maddaloni, and Linda J. Phillips

    Exposure to Free and Conjugated Forms of Bisphenol A and Triclosan among Pregnant Women in the MIREC Cohort

    Tye E. Arbuckle, Leonora Marro, Karelyn Davis, Mandy Fisher, Pierre Ayotte, Patrick Bélanger, Pierre Dumas, Alain LeBlanc, René Bérubé, Éric Gaudreau, Gilles Provencher, Elaine M. Faustman, Eric Vigoren, Adrienne S. Ettinger, Michael Dellarco, Susan MacPherson, and William D. Fraser

    In Utero and Childhood Polybrominated Diphenyl Ether Exposures and Body Mass at Age 7 Years: The CHAMACOS Study

    Ayca Erkin-Cakmak, Kim G. Harley, Jonathan Chevrier, Asa Bradman, Katherine Kogut, Karen Huen, and Brenda Eskenazi

    Measurement of Total and Free Urinary Phenol and Paraben Concentrations over the Course of Pregnancy: Assessing Reliability and Contamination of Specimens in the Norwegian Mother and Child Cohort Study

    Virginia T. Guidry, Matthew P. Longnecker, Heidi Aase, Merete Eggesbø, Pål Zeiner, Ted Reichborn-Kjennerud, Gun P. Knudsen, Randi J. Bertelsen, Xiaoyun Ye, Antonia M. Calafat, and Stephanie M. Engel

    Anthropometry in 5- to 9-Year-Old Greenlandic and Ukrainian Children in Relation to Prenatal Exposure to Perfluorinated Alkyl Substances

    Birgit Bjerre Høyer, Cecilia Høst Ramlau-Hansen, Martine Vrijheid, Damaskini Valvi, Henning Sloth Pedersen, Valentyna Zviezdai, Bo A.G. Jönsson, Christian H. Lindh, Jens Peter Bonde, and Gunnar Toft

    ADVANCE PUBLICATION | Associations of Perfluoroalkyl Substances (PFASs) with Lower Birth Weight: An Evaluation of Potential Confounding by Glomerular Filtration Rate Using a Physiologically Based Pharmacokinetic Model (PBPK)

    Marc-André Verner, Anne E. Loccisano, Nils-Halvdan Morken, Miyoung Yoon, Huali Wu, Robin McDougall, Mildred Maisonet, Michele Marcus, Reiko Kishi, Chihiro Miyashita, Mei-Huei Chen, Wu-Shiun Hsieh, Melvin E. Andersen, Harvey J. Clewell III, and Matthew P. Longnecker

    ADVANCE PUBLICATION | Prepubertal Serum Concentrations of Organochlorine Pesticides and Age at Sexual Maturity in Russian Boys

    Thuy Lam, Paige L. Williams, Mary M. Lee, Susan A. Korrick, Linda S. Birnbaum, Jane S. Burns, Oleg Sergeyev, Boris Revich, Larisa M. Altshul, Donald G. Patterson Jr., and Russ Hauser

    ADVANCE PUBLICATION | Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort

    Michelle M. Maresca, Lori A. Hoepner, Abeer Hassoun, Sharon E. Oberfield, Stephen J. Mooney, Antonia M. Calafat, Judyth Ramirez, Greg Freyer, Frederica P. Perera, Robin M. Whyatt, and Andrew G. Rundle

    ADVANCE PUBLICATION | Organochlorine Compounds and Ultrasound Measurements of Fetal Growth in the INMA Cohort (Spain)

    Maria-Jose Lopez-Espinosa, Mario Murcia, Carmen Iñiguez, Esther Vizcaino, Olga Costa, Ana Fernández-Somoano, Mikel Basterrechea, Aitana Lertxundi, Mònica Guxens, Mireia Gascon, Fernando Goñi-Irigoyen, Joan O. Grimalt, Adonina Tardón, and Ferran Ballester

    ADVANCE PUBLICATION | First-Trimester Urine Concentrations of Phthalate Metabolites and Phenols and Placenta miRNA Expression in a Cohort of U.S. Women

    Jessica LaRocca, Alexandra M. Binder, Thomas F. McElrath, and Karin B. Michels

    ADVANCE PUBLICATION | Prenatal Phthalate, Perfluoroalkyl Acid, and Organochlorine Exposures and Term Birth Weight in Three Birth Cohorts: Multi-Pollutant Models Based on Elastic Net Regression

    Virissa Lenters, Lützen Portengen, Anna Rignell-Hydbom, Bo A.G. Jönsson, Christian H. Lindh, Aldert H. Piersma, Gunnar Toft, Jens Peter Bonde, Dick Heederik, Lars Rylander, and Roel Vermeulen

    ADVANCE PUBLICATION | Birth Weight, Ethnicity, and Exposure to Trihalomethanes and Haloacetic Acids in Drinking Water during Pregnancy in the Born in Bradford Cohort

    Rachel B. Smith, Susan C. Edwards, Nicky Best, John Wright, Mark J. Nieuwenhuijsen, and Mireille B. Toledano

    Air Pollution: Particulate Matter, Smoke, Indoor Air open

    Sources of Fine Particulate Matter and Risk of Preterm Birth in Connecticut, 2000–2006: A Longitudinal Study

    Gavin Pereira, Michelle L. Bell, Hyung Joo Lee, Petros Koutrakis, and Kathleen Belanger

    Evaluating Potential Response-Modifying Factors for Associations between Ozone and Health Outcomes: A Weight-of-Evidence Approach

    Lisa C. Vinikoor-Imler, Elizabeth O. Owens, Jennifer L. Nichols, Mary Ross, James S. Brown, and Jason D. Sacks

    Prenatal Air Pollution Exposure and Newborn Blood Pressure

    Lenie van Rossem, Sheryl L. Rifas-Shiman, Steven J. Melly, Itai Kloog, Heike Luttmann-Gibson, Antonella Zanobetti, Brent A. Coull, Joel D. Schwartz, Murray A. Mittleman, Emily Oken, Matthew W. Gillman, Petros Koutrakis, and Diane R. Gold

    Blood Pressure and Same-Day Exposure to Air Pollution at School: Associations with Nano-Sized to Coarse PM in Children

    Nicky Pieters, Gudrun Koppen, Martine Van Poppel, Sofie De Prins, Bianca Cox, Evi Dons, Vera Nelen, Luc Int Panis, Michelle Plusquin, Greet Schoeters, and Tim S. Nawrot

    Air Pollution and Lung Function in Dutch Children: A Comparison of Exposure Estimates and Associations Based on Land Use Regression and Dispersion Exposure Modeling Approaches

    Meng Wang, Ulrike Gehring, Gerard Hoek, Menno Keuken, Sander Jonkers, Rob Beelen, Marloes Eeftens, Dirkje S. Postma, and Bert Brunekreef

    Differences in Birth Weight Associated with the 2008 Beijing Olympics Air Pollution Reduction: Results from a Natural Experiment

    David Q. Rich, Kaibo Liu, Jinliang Zhang, Sally W. Thurston, Timothy P. Stevens, Ying Pan, Cathleen Kane, Barry Weinberger, Pamela Ohman-Strickland, Tracey J. Woodruff, Xiaoli Duan, Vanessa Assibey-Mensah, and Junfeng Zhang

    ADVANCE PUBLICATION | Ambient Air Pollution and Newborn Size and Adiposity at Birth: Differences by Maternal Ethnicity (the Born in Bradford Study Cohort)

    Anna Schembari, Kees de Hoogh, Marie Pedersen, Payam Dadvand, David Martinez, Gerard Hoek, Emily S. Petherick, John Wright, and Mark J. Nieuwenhuijsen

    ADVANCE PUBLICATION | Elemental Constituents of Particulate Matter and Newborn’s Size in Eight European Cohorts

    Marie Pedersen, Ulrike Gehring, Rob Beelen, Meng Wang, Lise Giorgis-Allemand, Anne-Marie Nybo Andersen, Xavier Basagaña, Claire Bernard, Marta Cirach, Francesco Forastiere, Kees de Hoogh, Regina Gražulevičienė, Olena Gruzieva, Gerard Hoek, Aleksandra Jedynska, Claudia Klümper, Ingeborg M. Kooter, Ursula Krämer, Jaakko Kukkonen, Daniela Porta, Dirkje S. Postma, Ole Raaschou-Nielsen, Lenie van Rossem, Jordi Sunyer, Mette Sørensen, Ming-Yi Tsai, Tanja G. M. Vrijkotte, Michael Wilhelm, Mark J. Nieuwenhuijsen, Göran Pershagen, Bert Brunekreef, Manolis Kogevinas, and Rémy Slama

    Natural Gas and Fracking open

    Proximity to Natural Gas Wells and Reported Health Status: Results of a Household Survey in Washington County, Pennsylvania

    Peter M. Rabinowitz, Ilya B. Slizovskiy, Vanessa Lamers, Sally J. Trufan, Theodore R. Holford, James D. Dziura, Peter N. Peduzzi, Michael J. Kane, John S. Reif, Theresa R. Weiss, and Meredith H. Stowe

    Endotoxins, Food Toxins, and Water Toxins open

    A Prospective Study of Growth and Biomarkers of Exposure to Aflatoxin and Fumonisin during Early Childhood in Tanzania

    Candida P. Shirima, Martin E. Kimanya, Michael N. Routledge, Chou Srey, Joyce L. Kinabo, Hans-Ulrich Humpf, Christopher P. Wild, Yu-Kang Tu, and Yun Yun Gong

    Climate Change open

    EDITORIAL | Protecting Our Children from Climate Change

    Linda S. Birnbaum and Kimberly Thigpen Tart

    Summertime Acute Heat Illness in U.S. Emergency Departments from 2006 through 2010: Analysis of a Nationally Representative Sample

    Jeremy J. Hess, Shubhayu Saha, and George Luber

    Ambient Heat and Sudden Infant Death: A Case-Crossover Study Spanning 30 Years in Montreal, Canada

    Nathalie Auger, William D. Fraser, Audrey Smargiassi, and Tom Kosatsky

    Radiation open

    Background Ionizing Radiation and the Risk of Childhood Cancer: A Census-Based Nationwide Cohort Study

    Ben D. Spycher, Judith E. Lupatsch, Marcel Zwahlen, Martin Röösli, Felix Niggli, Michael A. Grotzer, Johannes Rischewski, Matthias Egger, and Claudia E. Kuehni for the Swiss Pediatric Oncology Group and the Swiss National Cohort Study Group

    Built Environment open

    Residential Greenness and Birth Outcomes: Evaluating the Influence of Spatially Correlated Built-Environment Factors

    Perry Hystad, Hugh W. Davies, Lawrence Frank, Josh Van Loon, Ulrike Gehring, Lillian Tamburic, and Michael Brauer

    Risks and Benefits of Green Spaces for Children: A Cross-Sectional Study of Associations with Sedentary Behavior, Obesity, Asthma, and Allergy

    Payam Dadvand, Cristina M. Villanueva, Laia Font-Ribera, David Martinez, Xavier Basagaña, Jordina Belmonte, Martine Vrijheid, Regina Gražulevičienė, Manolis Kogevinas, and Mark J. Nieuwenhuijsen

    Green and Blue Spaces and Behavioral Development in Barcelona Schoolchildren: The BREATHE Project

    Elmira Amoly, Payam Dadvand, Joan Forns, Mónica López-Vicente, Xavier Basagaña, Jordi Julvez, Mar Alvarez-Pedrerol, Mark J. Nieuwenhuijsen, and Jordi Sunyer

    Characteristics of Walkable Built Environments and BMI z-Scores in Children: Evidence from a Large Electronic Health Record Database

    Dustin T. Duncan, Mona Sharifi, Steven J. Melly, Richard Marshall, Thomas D. Sequist, Sheryl L. Rifas-Shiman, and Elsie M. Taveras

    Metro Nature, Environmental Health, and Economic Value

    Kathleen L. Wolf and Alicia S.T. Robbins

    Global Health open

    EDITORIAL | Jenny Pronczuk de Garbino: A Global Champion for Children’s Health

    Philip J. Landrigan and William A. Suk

    Children’s Health in Latin America: The Influence of Environmental Exposures

    Amalia Laborde, Fernando Tomasina, Fabrizio Bianchi, Marie-Noel Bruné, Irena Buka, Pietro Comba, Lilian Corra, Liliana Cori, Christin Maria Duffert, Raul Harari, Ivano Iavarone, Melissa A. McDiarmid, Kimberly A. Gray, Peter D. Sly, Agnes Soares, William A. Suk, and Philip J. Landrigan

    First Steps toward Harmonized Human Biomonitoring in Europe: Demonstration Project to Perform Human Biomonitoring on a European Scale

    Elly Den Hond, Eva Govarts, Hanny Willems, Roel Smolders, Ludwine Casteleyn, Marike Kolossa-Gehring, Gerda Schwedler, Margarete Seiwert, Ulrike Fiddicke, Argelia Castaño, Marta Esteban, Jürgen Angerer, Holger M. Koch, Birgit K. Schindler, Ovnair Sepai, Karen Exley, Louis Bloemen, Milena Horvat, Lisbeth E. Knudsen, Anke Joas, Reinhard Joas, Pierre Biot, Dominique Aerts, Gudrun Koppen, Andromachi Katsonouri, Adamos Hadjipanayis, Andrea Krskova, Marek Maly, Thit A. Mørck, Peter Rudnai, Szilvia Kozepesy, Maurice Mulcahy, Rory Mannion, Arno C. Gutleb, Marc E. Fischer, Danuta Ligocka, Marek Jakubowski, M. Fátima Reis, Sónia Namorado, Anca Elena Gurzau, Ioana-Rodica Lupsa, Katarina Halzlova, Michal Jajcaj, Darja Mazej, Janja Snoj Tratnik, Ana López, Estrella Lopez, Marika Berglund, Kristin Larsson, Andrea Lehmann, Pierre Crettaz, and Greet Schoeters
  • Biomarkers and Biomonitoring open

    BRIEF COMMUNICATION | Optimal Exposure Biomarkers for Nonpersistent Chemicals in Environmental Epidemiology

    Antonia M. Calafat, Matthew P. Longnecker, Holger M. Koch, Shanna H. Swan, Russ Hauser, Lynn R. Goldman, Bruce P. Lanphear, Ruthann A. Rudel, Stephanie M. Engel, Susan L. Teitelbaum, Robin M. Whyatt, and Mary S. Wolff

    Maternal Arsenic Exposure, Arsenic Methylation Efficiency, and Birth Outcomes in the Biomarkers of Exposure to ARsenic (BEAR) Pregnancy Cohort in Mexico

    Jessica E. Laine, Kathryn A. Bailey, Marisela Rubio-Andrade, Andrew F. Olshan, Lisa Smeester, Zuzana Drobná, Amy H. Herring, Miroslav Stýblo, Gonzalo G. García-Vargas, and Rebecca C. Fry

    Urinary Phthalate Metabolites and Biomarkers of Oxidative Stress in Pregnant Women: A Repeated Measures Analysis

    Kelly K. Ferguson, Thomas F. McElrath, Yin-Hsiu Chen, Bhramar Mukherjee, and John D. Meeker

    Variation in Urinary Flow Rates According to Demographic Characteristics and Body Mass Index in NHANES: Potential Confounding of Associations between Health Outcomes and Urinary Biomarker Concentrations

    Sean M. Hays, Lesa L. Aylward, and Benjamin C. Blount

    Epigenetics open

    Identification of DNA Methylation Changes in Newborns Related to Maternal Smoking during Pregnancy

    Christina A. Markunas, Zongli Xu, Sophia Harlid, Paul A. Wade, Rolv T. Lie, Jack A. Taylor, and Allen J. Wilcox

    Prenatal Exposure to Maternal Cigarette Smoking and DNA Methylation: Epigenome-Wide Association in a Discovery Sample of Adolescents and Replication in an Independent Cohort at Birth through 17 Years of Age

    Ken W.K. Lee, Rebecca Richmond, Pingzhao Hu, Leon French, Jean Shin, Celine Bourdon, Eva Reischl, Melanie Waldenberger, Sonja Zeilinger, Tom Gaunt, Wendy McArdle, Susan Ring, Geoff Woodward, Luigi Bouchard, Daniel Gaudet, George Davey Smith, Caroline Relton, Tomas Paus, and Zdenka Pausova

    Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother–Child Study (NewGeneris)

    Marie Pedersen, Michelle A. Mendez, Bernadette Schoket, Roger W. Godschalk, Ana Espinosa, Anette Landström, Cristina M. Villanueva, Domenico F. Merlo, Eleni Fthenou, Esther Gracia-Lavedan, Frederik-J. van Schooten, Gerard Hoek, Gunnar Brunborg, Helle M. Meltzer, Jan Alexander, Jeanette K. Nielsen, Jordi Sunyer, John Wright, Katalin Kovács, Kees de Hoogh, Kristine B. Gutzkow, Laura J. Hardie, Leda Chatzi, Lisbeth E. Knudsen, Lívia Anna, Matthias Ketzel, Margaretha Haugen, Maria Botsivali, Mark J. Nieuwenhuijsen, Marta Cirach, Mireille B. Toledano, Rachel B. Smith, Sarah Fleming, Silvia Agramunt, Soterios A. Kyrtopoulos, Viktória Lukács, Jos C. Kleinjans, Dan Segerbäck, and Manolis Kogevinas

    Placental DNA Methylation Related to Both Infant Toenail Mercury and Adverse Neurobehavioral Outcomes

    Jennifer Z.J. Maccani, Devin C. Koestler, Barry Lester, E. Andrés Houseman, David A. Armstrong, Karl T. Kelsey, and Carmen J. Marsit

    In Utero Fine Particle Air Pollution and Placental Expression of Genes in the Brain-Derived Neurotrophic Factor Signaling Pathway: An ENVIRONAGE Birth Cohort Study

    Nelly D. Saenen, Michelle Plusquin, Esmée Bijnens, Bram G. Janssen, Wilfried Gyselaers, Bianca Cox, Frans Fierens, Geert Molenberghs, Joris Penders, Karen Vrijens, Patrick De Boever, and Tim S. Nawrot

    Methodologies open

    The Navigation Guide Systematic Review Methodology: A Rigorous and Transparent Method for Translating Environmental Health Science into Better Health Outcomes

    Tracey J. Woodruff and Patrice Sutton

    The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Systematic Review of Nonhuman Evidence for PFOA Effects on Fetal Growth

    Erica Koustas, Juleen Lam, Patrice Sutton, Paula I. Johnson, Dylan S. Atchley, Saunak Sen, Karen A. Robinson, Daniel A. Axelrad, and Tracey J. Woodruff

    The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Systematic Review of Human Evidence for PFOA Effects on Fetal Growth

    Paula I. Johnson, Patrice Sutton, Dylan S. Atchley, Erica Koustas, Juleen Lam, Saunak Sen, Karen A. Robinson, Daniel A. Axelrad, and Tracey J. Woodruff

    The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Integration of Animal and Human Evidence for PFOA Effects on Fetal Growth

    Juleen Lam, Erica Koustas, Patrice Sutton, Paula I. Johnson, Dylan S. Atchley, Saunak Sen, Karen A. Robinson, Daniel A. Axelrad, and Tracey J. Woodruff

    Examination of the Safety of Pediatric Vaccine Schedules in a Non-Human Primate Model: Assessments of Neurodevelopment, Learning, and Social Behavior

    Britni Curtis, Noelle Liberato, Megan Rulien, Kelly Morrisroe, Caroline Kenney, Vernon Yutuc, Clayton Ferrier, C. Nathan Marti, Dorothy Mandell, Thomas M. Burbacher, Gene P. Sackett, and Laura Hewitson

    ADVANCE PUBLICATION | Bidirectional Transfer Study of Polystyrene Nanoparticles across the Placental Barrier in an ex Vivo Human Placental Perfusion Model

    Stefanie Grafmueller, Pius Manser, Liliane Diener, Pierre-André Diener, Xenia Maeder-Althaus, Lionel Maurizi, Wolfram Jochum, Harald F. Krug, Tina Buerki-Thurnherr, Ursula von Mandach, and Peter Wick

    ADVANCE PUBLICATION | Reducing Periconceptional Methylmercury Exposure: Cost–Utility Analysis for a Proposed Screening Program for Women Planning a Pregnancy in Ontario, Canada

    Janet Gaskin, Colin Rennie, and Doug Coyle

    ADVANCE PUBLICATION | Impact of Exposure Uncertainty on the Association between Perfluorooctanoate and Preeclampsia in the C8 Health Project Population

    Raghavendhran Avanasi, Hyeong-Moo Shin, Verónica M. Vieira, David A. Savitz, and Scott M. Bartell
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