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Featured Children’s Health Articles

From the EHP Editors

Flame retardants can be found throughout commonly used products such as furniture, cars, mattresses, building materials, and electronic equipment, exposing most people to polybrominated diphenyl ethers (PBDEs). In a systematic review and meta-analysis, Lam et al. reviewed relevant studies and examined developmental exposure to PBDEs in relation to intelligence and attention-related behavior problems. When they combined the results of four similar studies, their overall estimate suggested that prenatal exposure to PBDEs was associated with lower IQ. Although some studies reported associations with ADHD and attention-related behaviors in the children, the authors concluded that, overall, the current evidence is not conclusive.

Photograph of a young girl playing on a couch.
© Evgeny Atamanenko/Shutterstock

Developmental PBDE Exposure and IQ/ADHD in Childhood: A Systematic Review and Meta-analysis

Photograph of a family eating fruit
© Hrecheniuk Oleksii/Shutterstock

Prenatal Organophosphorus Pesticide Exposure and Child Neurodevelopment at 24 Months: An Analysis of Four Birth Cohorts

From the EHP Editors

Engel et al. pooled data from four birth cohorts to assess how exposure to organophosphorus pesticides may affect neurodevelopment at 24 months. Findings from the individual studies differed, possibly because of differences among the study populations in factors such as socioeconomic status and race/ethnicity. The authors cautioned that these differences, combined with differences in the types of exposure and outcome measurements used by each study, make it difficult to interpret estimates for the combined data from all four studies. From the combined data, the authors estimated that a 10-fold increase in prenatal exposure was associated with a 1-point decrease in the Bayley Mental Development Index. However, they noted that the combined estimate should be interpreted with caution given the differences among the studies.

Children’s Lead Exposure: A Multimedia Modeling Analysis to Guide Public Health Decision-Making
Prenatal Exposure to Mercury: Associations with Global DNA Methylation and Hydroxymethylation in Cord Blood and in Childhood
Exposure to Low Levels of Lead in Utero and Umbilical Cord Blood DNA Methylation in Project Viva: An Epigenome-Wide Association Study
Early-Life Phthalate Exposure and Adiposity at 8 Years of Age
Combined Prenatal Pesticide Exposure and Folic Acid Intake in Relation to Autism Spectrum Disorder
In Utero Exposure to Select Phenols and Phthalates and Respiratory Health in Five-Year-Old Boys: A Prospective Study
Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization
Elemental Sulfur Use and Associations with Pediatric Lung Function and Respiratory Symptoms in an Agricultural Community (California, USA)
Serum Vaccine Antibody Concentrations in Adolescents Exposed to Perfluorinated Compounds
Weekly Personal Ozone Exposure and Respiratory Health in a Panel of Greek Schoolchildren

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