Open access
Research Article
1 May 2000

Air pollution and daily hospital admissions in metropolitan Los Angeles.

Publication: Environmental Health Perspectives
Volume 108, Issue 5
Pages 427 - 434


We used daily time-series analysis to evaluate associations between ambient carbon monoxide, nitrogen dioxide, particulate matter [less than and equal to] 10 microm in aerodynamic diameter (PM(10)), or ozone concentrations, and hospital admissions for cardiopulmonary illnesses in metropolitan Los Angeles during 1992-1995. We performed Poisson regressions for the entire patient population and for subgroups defined by season, region, or personal characteristics, allowing for effects of temporal variation, weather, and autocorrelation. CO showed the most consistently significant (p<0.05) relationships to cardiovascular admissions. A wintertime 25th-75th percentile increase in CO (1.1-2.2 ppm) predicted an increase of 4% in cardiovascular admissions. NO(2), and, to a lesser extent, PM(10) tracked CO and showed similar associations with cardiovascular disease, but O(3) was negatively or nonsignificantly associated. No significant demographic differences were found, although increased cardiovascular effects were suggested in diabetics, in whites and blacks (relative to Hispanics and Asians), and in persons older than 65 years of age. Pulmonary disease admissions associated more with NO(2) and PM(10) than with CO. Pulmonary effects were generally smaller than cardiovascular effects and were more sensitive to the choice of model. We conclude that in Los Angeles, atmospheric stagnation with high primary (CO/NO(2)/PM(10)) pollution, most common in autumn/winter, increases the risk of hospitalization for cardiopulmonary illness. Summer photochemical pollution (high O(3)) apparently presents less risk.

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Information & Authors


Published In

Environmental Health Perspectives
Volume 108Issue 5May 2000
Pages: 427 - 434
PubMed: 10811569


Published online: 1 May 2000



W S Linn
Rancho Los Amigos National Rehabilitation Center, Downey, California 90242, USA. [email protected]
Y Szlachcic
Rancho Los Amigos National Rehabilitation Center, Downey, California 90242, USA. [email protected]
H Gong, Jr
Rancho Los Amigos National Rehabilitation Center, Downey, California 90242, USA. [email protected]
P L Kinney
Rancho Los Amigos National Rehabilitation Center, Downey, California 90242, USA. [email protected]
K T Berhane
Rancho Los Amigos National Rehabilitation Center, Downey, California 90242, USA. [email protected]

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