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Abstracts
23 August 2021
ISEE 2021: 33rd Annual Conference of the International Society of Environmental Epidemiology

Urban Environment and Growth and Obesity in Preschool Children from Six European Birth Cohorts

Publication: ISEE Conference Abstracts
Volume 2021, Issue 1

Abstract

BACKGROUND AND AIM: Urban environmental exposures have been investigated separately in relation to growth and childhood obesity. In this study we aim to determine which prenatal and postnatal outdoor exposures are associated with childhood BMI, weight and height at age 3-4 years. METHODS: Height and weight were measured in 11,325 children aged 3-4 years from a multi-centre European cohort (France, Greece, Lithuania, Norway, Spain, and UK). BMI was calculated using the formula weight/height². Age-and-sex–standardized {z}-scores were calculated for height, weight and BMI. Urban environment exposures were estimated during pregnancy and childhood, including air pollution, built environment, green spaces, traffic, noise, meteorology, and socioeconomic deprivation index. Exposure-wide association study was performed using multiple single exposure linear regression models and accounting for multiple testing. RESULTS:Non linear associations were observed between exposure to Normalized Difference Vegetation Index (NDVI), a measure of greeness, and the outcomes leading to its categorization into tertiles. Pregnancy and postnatal NDVI in the first tertile were associated with greater height compared to the reference (second tertile), and remained statistically significant after correction for multiple testing (prenatal corrected {p}-value threshold for significance = 0.002; postnatal corrected {p}-value = 0.003). Other prenatal and postnatal markers of the urban environment such as walkability, building density and land use, nitrogen dioxide and fine particles were also associated with greater height, but were no longer statistically significant after correction for multiple testing. Fine particles during pregnancy were associated with higher BMI, and prenatal NDVI in the first tertile and air pollution were also associated with higher weight, but the {p}-values for these associations were above the corrected threshold for multiple testing. CONCLUSIONS:Living in a less green and more densely built and walkable area may affect preschool height in a positve manner. KEYWORDS: External exposome, Green space, Built environment, Children's environmental health, Obesity and metabolic disorders

Information & Authors

Information

Published In

ISEE Conference Abstracts
Volume 2021Issue 123 August 2021

History

Published online: 23 August 2021

Authors

Affiliations

Serena Fossati
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.
Sandra Marquez
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.
Charline Warembourg
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.
Xavier Basagaña
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.
Montserrat de Castro
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.
Silvia Fernandez
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.
Lea Maitre
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.
Jose Urquiza
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.
Theano Roumeliotaki
Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.
Marina Vafeiadi
Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece.
Barbara Heude
Center of Research in Epidemiology and Statistics, INSERM, INRAe, University of Paris, Paris, France.
Remy Slama
Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, INSERM, CNRS, University Grenoble Alpes, Institute for Advanced Biosciences (IAB), U1209 Joint Research Center, Grenoble, France.
Sandra Andrušaitytė
Department of Environmental Sciences, Vytauto Didžiojo Universitetas, Kaunas, Lithuania.
Regina Gražulevičienė
Department of Environmental Sciences, Vytauto Didžiojo Universitetas, Kaunas, Lithuania.
Rosemary R. C. McEachan
Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, United Kingdom.
Oliver Robinson
MRC Centre for Environment and Health, Imperial College London, London, United Kingdom.
Line Småstuen Haug
Norwegian Institute of Public Health, Oslo, Norway.
Cathrine Thomssen
Norwegian Institute of Public Health, Oslo, Norway.
John Wright
Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, United Kingdom.
Lida Chatzi
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA; Department of Complex Genetics and Epidemiology, CAPHRI School for Public Health and Primary Care, University of Maastricht, Maastricht, the Netherlands.
Mark Nieuwenhuijsen
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.
Martine Vrijheid1
ISGlobal, Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; Consortium for Biomedical Research in Epidemiology & Public Health (CIBER Epidemiología y Salud Pública - CIBERESP), Madrid, Spain.

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