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Widely Used Pesticides with Previously Unknown Endocrine Activity Revealed as in Vitro Antiandrogens
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- Cited bySvanholm S, Roza M, Marini D, Brouard V, Karlsson O and Berg C (2023) Pubertal sexual development and endpoints for disrupted spermatogenesis in the model Xenopus tropicalis, Reproductive Toxicology, 10.1016/j.reprotox.2023.108435, 120, (108435), Online publication date: 1-Sep-2023.Lukić Bilela L, Matijošytė I, Krutkevičius J, Alexandrino D, Safarik I, Burlakovs J, Gaudêncio S and Carvalho M (2023) Impact of per- and polyfluorinated alkyl substances (PFAS) on the marine environment: Raising awareness, challenges, legislation, and mitigation approaches under the One Health concept, Marine Pollution Bulletin, 10.1016/j.marpolbul.2023.115309, 194, (115309), Online publication date: 1-Sep-2023.Jeong D, Jung D, Jang C, Kim U, Park Y, Park Y and Lee H (2023) Chlorpropham, a carbamate ester herbicide, has an endocrine-disrupting potential by inhibiting the homodimerization of human androgen receptor, Environmental Pollution, 10.1016/j.envpol.2023.121437, 325, (121437), Online publication date: 1-May-2023.Castiello F, Suárez B, Gómez-Vida J, Torrent M, Fernández M, Olea N and Freire C (2023) Exposure to non-persistent pesticides and sexual maturation of Spanish adolescent males, Chemosphere, 10.1016/j.chemosphere.2023.138350, 324, (138350), Online publication date: 1-May-2023.Eom S, Lim J, Ji S, Song J, Yoon J, Jeon H and Ryu S (2023) Investigation of Fludioxonil Reduction Using Non-Thermal Atmospheric Plasma through Experimental Simulation, Agriculture, 10.3390/agriculture13030727, 13:3, (727)Ma Y, Taxvig C, Rodríguez-Carrillo A, Mustieles V, Reiber L, Kiesow A, Löbl N, Fernández M, Hansen T, Valente M, Kolossa-Gehring M, David M and Vinggaard A (2023) Human risk associated with exposure to mixtures of antiandrogenic chemicals evaluated using in vitro hazard and human biomonitoring data, Environment International, 10.1016/j.envint.2023.107815, 173, (107815), Online publication date: 1-Mar-2023.Huang Y, Law J and Leung K (2023) The quest for metabolic biomarkers of agrochemicals exposure via in vitro studies and suspect screening, Science of The Total Environment, 10.1016/j.scitotenv.2022.160701, 861, (160701), Online publication date: 1-Feb-2023.Chen X, Hirano M, Ishibashi H, Lee J, Kawai Y and Kubota A (2023) Efficient in vivo and in silico assessments of antiandrogenic potential in zebrafish, Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 10.1016/j.cbpc.2022.109513, 264, (109513), Online publication date: 1-Feb-2023.Guimarães J, Bracchi I, Pinheiro C, Moreira N, Coelho C, Pestana D, Prucha M, Martins C, Domingues V, Delerue-Matos C, Dias C, Azevedo L, Calhau C, Leite J, Ramalho C, Keating E and Fernandes V (2023) Association of 3-Phenoxybenzoic Acid Exposure during Pregnancy with Maternal Outcomes and Newborn Anthropometric Measures: Results from the IoMum Cohort Study, Toxics, 10.3390/toxics11020125, 11:2, (125)Akkam Y, Omari D, Alhmoud H, Alajmi M, Akkam N and Aljarrah I (2023) Assessment of Xenoestrogens in Jordanian Water System: Activity and Identification, Toxics, 10.3390/toxics11010063, 11:1, (63)Boberg J, Johansson H, Franssen D, Draskau M, Christiansen S, Cramer J, Pedersen M, Parent A and Svingen T (2023) Exposure to the pesticides linuron, dimethomorph and imazalil alters steroid hormone profiles and gene expression in developing rat ovaries, Toxicology Letters, 10.1016/j.toxlet.2022.11.010, 373, (114-122), Online publication date: 1-Jan-2023.Castiello F, Suárez B, Beneito A, Lopez-Espinosa M, Santa-Marina L, Lertxundi A, Tardón A, Riaño-Galán I, Casas M, Vrijheid M, Olea N, Fernández M and Freire C (2023) Childhood exposure to non-persistent pesticides and pubertal development in Spanish girls and boys: Evidence from the INMA (Environment and Childhood) cohort, Environmental Pollution, 10.1016/j.envpol.2022.120571, 316, (120571), Online publication date: 1-Jan-2023.Abajue M and Gbarakoro T (2023) Prospects of Insect Farming for Food Security, Environmental Sustainability, and as an Alternative to Agrochemical Use One Health Implications of Agrochemicals and their Sustainable Alternatives, 10.1007/978-981-99-3439-3_21, (565-600), .Go R, Lee H, Kim C, Kim S and Choi K (2022) A fungicide, fenhexamid, is involved in the migration and angiogenesis in breast cancer cells expressing estrogen receptors, Life Sciences, 10.1016/j.lfs.2022.120754, 305, (120754), Online publication date: 1-Sep-2022.Dopavogui L, Cadoret F, Loison G, El Fouikar S, Frenois F, Giton F, Ellero-Simatos S, Lasserre F, Polizzi A, Rives C, Loiseau N, Léandri R, Gatimel N and Gamet-Payrastre L (2022) Pre- and Postnatal Dietary Exposure to a Pesticide Cocktail Disrupts Ovarian Functions in 8-Week-Old Female Mice, International Journal of Molecular Sciences, 10.3390/ijms23147525, 23:14, (7525)Bebek Markovinović A, Putnik P, Duralija B, Krivohlavek A, Ivešić M, Mandić Andačić I, Palac Bešlić I, Pavlić B, Lorenzo J and Bursać Kovačević D (2022) Chemometric Valorization of Strawberry (Fragaria x ananassa Duch.) cv. ‘Albion’ for the Production of Functional Juice: The Impact of Physicochemical, Toxicological, Sensory, and Bioactive Value, Foods, 10.3390/foods11050640, 11:5, (640)Montgomery K, Brar G and Krishnan V (2021) Metabolomics Study at the Postharvest Conditions of Cold Storage and Fungicide (Imazalil Sulfate) Treatment in Navel Oranges and Clementine Mandarins, ACS Agricultural Science & Technology, 10.1021/acsagscitech.1c00169, 2:1, (79-89), Online publication date: 21-Feb-2022.Al-Thomali A, Tag H, Mohammadein A, El-Shenawy N and El-Naggar M (2022) Mercaptophos impacts on redox status biomarkers of common carp (Cyprinus carpio) as an endocrine disruptor, Aquaculture Reports, 10.1016/j.aqrep.2021.100959, 22, (100959), Online publication date: 1-Feb-2022.Knapke E, Magalhaes D, Dalvie M, Mandrioli D and Perry M (2022) Environmental and occupational pesticide exposure and human sperm parameters: A Navigation Guide review, Toxicology, 10.1016/j.tox.2021.153017, 465, (153017), Online publication date: 1-Jan-2022.Alexandrino D, Almeida C, Mucha A and Carvalho M (2022) Revisiting pesticide pollution: The case of fluorinated pesticides, Environmental Pollution, 10.1016/j.envpol.2021.118315, 292, (118315), Online publication date: 1-Jan-2022.Bhanse P, Maitreya A, Patil A, Yesankar P, Singh L and Qureshi A (2022) Agrochemicals: Provenance, Environmental Fate, and Remediation Measures Agrochemicals in Soil and Environment, 10.1007/978-981-16-9310-6_2, (25-59), .Zahran E, Elbahnaswy S, Mamdouh A and El‐Matbouli M (2021) Xenosteroids in aquaculture with special consideration to Lake Manzala (Northern delta lake, Egypt): Types, sources and mechanism of action, Aquaculture Research, 10.1111/are.15504, 52:12, (5962-5977), Online publication date: 1-Dec-2021.Nettore I, Franchini F, Palatucci G, Macchia P and Ungaro P (2021) Epigenetic Mechanisms of Endocrine-Disrupting Chemicals in Obesity, Biomedicines, 10.3390/biomedicines9111716, 9:11, (1716)Tanaka T, Suzuki J, Inomata A and Moriyasu T (2021) Combined effects of maternal exposure to fungicides on behavioral development in F 1 ‐generation mice: 3. Fixed‐dose study of imazalil , Birth Defects Research, 10.1002/bdr2.1956, 113:19, (1390-1406), Online publication date: 15-Nov-2021.Schwartz C, Christiansen S, Hass U, Ramhøj L, Axelstad M, Löbl N and Svingen T (2021) On the Use and Interpretation of Areola/Nipple Retention as a Biomarker for Anti-androgenic Effects in Rat Toxicity Studies, Frontiers in Toxicology, 10.3389/ftox.2021.730752, 3Kassotis C, Hoffman K, Völker J, Pu Y, Veiga-Lopez A, Kim S, Schlezinger J, Bovolin P, Cottone E, Saraceni A, Scandiffio R, Atlas E, Leingartner K, Krager S, Tischkau S, Ermler S, Legler J, Chappell V, Fenton S, Mesmar F, Bondesson M, Fernández M and Stapleton H (2021) Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study, Toxicology, 10.1016/j.tox.2021.152900, 461, (152900), Online publication date: 1-Sep-2021.Samaras A, Karaoglanidis G and Tzelepis G (2021) Insights into the multitrophic interactions between the biocontrol agent Bacillus subtilis MBI 600, the pathogen Botrytis cinerea and their plant host, Microbiological Research, 10.1016/j.micres.2021.126752, 248, (126752), Online publication date: 1-Jul-2021.Karlsson O, Svanholm S, Eriksson A, Chidiac J, Eriksson J, Jernerén F and Berg C (2021) Pesticide-induced multigenerational effects on amphibian reproduction and metabolism, Science of The Total Environment, 10.1016/j.scitotenv.2021.145771, 775, (145771), Online publication date: 1-Jun-2021.Freire C, Suárez B, Vela-Soria F, Castiello F, Reina-Pérez I, Andersen H, Olea N and Fernández M (2021) Urinary metabolites of non-persistent pesticides and serum hormones in Spanish adolescent males, Environmental Research, 10.1016/j.envres.2021.111016, 197, (111016), Online publication date: 1-Jun-2021.Suárez B, Vela-Soria F, Castiello F, Olivas-Martinez A, Acuña-Castroviejo D, Gómez-Vida J, Olea N, Fernández M and Freire C (2021) Organophosphate pesticide exposure, hormone levels, and interaction with PON1 polymorphisms in male adolescents, Science of The Total Environment, 10.1016/j.scitotenv.2020.144563, 769, (144563), Online publication date: 1-May-2021.Molomo R, Basera W, Chetty-Mhlanga S, Fuhrimann S, Mugari M, Wiesner L, Röösli M and Dalvie M (2021) Relation between organophosphate pesticide metabolite concentrations with pesticide exposures, socio-economic factors and lifestyles: A cross-sectional study among school boys in the rural Western Cape, South Africa, Environmental Pollution, 10.1016/j.envpol.2021.116660, 275, (116660), Online publication date: 1-Apr-2021.Go R, Kim C, Lee S, Lee H and Choi K (2021) Fenhexamid induces cancer growth and survival via estrogen receptor-dependent and PI3K-dependent pathways in breast cancer models, Food and Chemical Toxicology, 10.1016/j.fct.2021.112000, 149, (112000), Online publication date: 1-Mar-2021.Jin C, Yuan X, Wang C, Fu Z and Jin Y (2021) Maternal exposure to imazalil disrupts intestinal barrier and bile acids enterohepatic circulation tightly related IL-22 expression in F0, F1 and F2 generations of mice, Journal of Hazardous Materials, 10.1016/j.jhazmat.2020.123668, 403, (123668), Online publication date: 1-Feb-2021.Hu X, Shi W, Wei S, Zhang X and Yu H (2021) Identification of (anti-)androgenic activities and risks of sludges from industrial and domestic wastewater treatment plants, Environmental Pollution, 10.1016/j.envpol.2020.115716, 268, (115716), Online publication date: 1-Jan-2021.Unuofin J, Aladekoyi O and Odeniyi O (2021) Microbiome stimulants for crops: indicators for an economically proficient sustainable agriculture Microbiome Stimulants for Crops, 10.1016/B978-0-12-822122-8.00027-3, (405-416), .Bernabò I, Guardia A, Macirella R, Sesti S, Tripepi S and Brunelli E (2020) Tissues injury and pathological changes in Hyla intermedia juveniles after chronic larval exposure to tebuconazole, Ecotoxicology and Environmental Safety, 10.1016/j.ecoenv.2020.111367, 205, (111367), Online publication date: 1-Dec-2020.Tanaka T, Suzuki T, Inomata A and Moriyasu T (2020) Combined effects of maternal exposure to fungicides on behavioral development in F 1 ‐generation mice: 2. Fixed‐dose study of thiabendazole , Birth Defects Research, 10.1002/bdr2.1793, 112:20, (1809-1824), Online publication date: 1-Dec-2020.Orton F, Svanholm S, Jansson E, Carlsson Y, Eriksson A, Uren Webster T, McMillan T, Leishman M, Verbruggen B, Economou T, Tyler C, Berg C and Anbazhagan R (2020) A laboratory investigation into features of morphology and physiology for their potential to predict reproductive success in male frogs, PLOS ONE, 10.1371/journal.pone.0241625, 15:11, (e0241625)Scholze M, Taxvig C, Kortenkamp A, Boberg J, Christiansen S, Svingen T, Lauschke K, Frandsen H, Ermler S, Hermann S, Pedersen M, Lykkeberg A, Axelstad M and Vinggaard A (2020) Quantitative in Vitro to in Vivo Extrapolation (QIVIVE) for Predicting Reduced Anogenital Distance Produced by Anti-Androgenic Pesticides in a Rodent Model for Male Reproductive Disorders, Environmental Health Perspectives, 128:11, Online publication date: 1-Nov-2020.Ren X, Kuo Y and Blumberg B (2020) Agrochemicals and obesity, Molecular and Cellular Endocrinology, 10.1016/j.mce.2020.110926, 515, (110926), Online publication date: 1-Sep-2020.Trudeau V, Thomson P, Zhang W, Reynaud S, Navarro-Martin L and Langlois V (2020) Agrochemicals disrupt multiple endocrine axes in amphibians, Molecular and Cellular Endocrinology, 10.1016/j.mce.2020.110861, 513, (110861), Online publication date: 1-Aug-2020.Alexandrino D, Mucha A, Almeida C and Carvalho M (2020) Microbial degradation of two highly persistent fluorinated fungicides - epoxiconazole and fludioxonil, Journal of Hazardous Materials, 10.1016/j.jhazmat.2020.122545, 394, (122545), Online publication date: 1-Jul-2020.Vlassi E, Bempelou E, Liapis K and Arapis G (2020) Consumer safety evaluation after monitoring of endocrine disruptor pesticide residues: a case study of Thessaly, Central Greece, Toxicological & Environmental Chemistry, 10.1080/02772248.2020.1770256, 102:1-4, (105-123), Online publication date: 20-Apr-2020.Abd-Elhaleem Z (2020) Pesticide residues in tomato and tomato products marketed in Majmaah province, KSA, and their impact on human health, Environmental Science and Pollution Research, 10.1007/s11356-019-07573-x, 27:8, (8526-8534), Online publication date: 1-Mar-2020.Zhou Q, Fu M, Xu M, Chen X, Qiu J, Wang F, Yan R, Wang J, Zhao S, Xin X and Chen L (2020) Application of antagonist Bacillus amyloliquefaciens NCPSJ7 against Botrytis cinerea in postharvest Red Globe grapes , Food Science & Nutrition, 10.1002/fsn3.1434, 8:3, (1499-1508), Online publication date: 1-Mar-2020.Tanaka T, Suzuki T, Inomata A and Moriyasu T (2019) Combined effects of maternal exposure to fungicides on behavioral development in F 1 ‐generation mice: 1. Several dose study of both imazalil and thiabendazole , Birth Defects Research, 10.1002/bdr2.1613, 112:2, (141-161), Online publication date: 15-Jan-2020.Nistal M, Paniagua R and González-Peramato P (2020) Nonneoplastic Diseases of the Testis Urologic Surgical Pathology, 10.1016/B978-0-323-54941-7.00012-8, (549-730.e81), .Singh S, Singh S, Bhawana and Vig A (2020) Earthworm-assisted bioremediation of agrochemicals Agrochemicals Detection, Treatment and Remediation, 10.1016/B978-0-08-103017-2.00013-1, (307-327), .Ma M, Chen C, Yang G, Wang Y, Wang T, Li Y and Qian Y (2019) Combined anti-androgenic effects of mixtures of agricultural pesticides using in vitro and in silico methods, Ecotoxicology and Environmental Safety, 10.1016/j.ecoenv.2019.109652, 186, (109652), Online publication date: 1-Dec-2019.Apell J, Pflug N and McNeill K (2019) Photodegradation of Fludioxonil and Other Pyrroles: The Importance of Indirect Photodegradation for Understanding Environmental Fate and Photoproduct Formation, Environmental Science & Technology, 10.1021/acs.est.9b03948, 53:19, (11240-11250), Online publication date: 1-Oct-2019.Thomas P and Dong J (2019) Novel mechanism of endocrine disruption by fungicides through binding to the membrane androgen receptor, ZIP9 (SLC39A9), and antagonizing rapid testosterone induction of the intrinsic apoptotic pathway, Steroids, 10.1016/j.steroids.2019.05.007, 149, (108415), Online publication date: 1-Sep-2019.Santos R, Piccoli C, Cremonese C and Freire C (2019) Thyroid and reproductive hormones in relation to pesticide use in an agricultural population in Southern Brazil, Environmental Research, 10.1016/j.envres.2019.03.050, 173, (221-231), Online publication date: 1-Jun-2019.Dopp E, Pannekens H, Itzel F and Tuerk J (2019) Effect-based methods in combination with state-of-the-art chemical analysis for assessment of water quality as integrated approach, International Journal of Hygiene and Environmental Health, 10.1016/j.ijheh.2019.03.001, 222:4, (607-614), Online publication date: 1-May-2019.Boccard J, Tonoli D, Strajhar P, Jeanneret F, Odermatt A and Rudaz S (2019) Removal of batch effects using stratified subsampling of metabolomic data for in vitro endocrine disruptors screening, Talanta, 10.1016/j.talanta.2018.11.019, 195, (77-86), Online publication date: 1-Apr-2019.Jin C, Zhang R, Fu Z and Jin Y (2019) Maternal exposure to imazalil disrupts the endocrine system in F1 generation mice, Molecular and Cellular Endocrinology, 10.1016/j.mce.2019.03.002, 486, (105-112), Online publication date: 1-Apr-2019.Szuroczki D, Koprivnikar J and Baker R (2019) Effects of dietary antioxidants and environmental stressors on immune function and condition in Lithobates (Rana) sylvaticus, Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 10.1016/j.cbpa.2018.11.017, 229, (25-32), Online publication date: 1-Mar-2019.Calvo-Garrido C, Roudet J, Aveline N, Davidou L, Dupin S and Fermaud M (2019) Microbial Antagonism Toward Botrytis Bunch Rot of Grapes in Multiple Field Tests Using One Bacillus ginsengihumi Strain and Formulated Biological Control Products, Frontiers in Plant Science, 10.3389/fpls.2019.00105, 10Ye X and Liu J (2019) Effects of pyrethroid insecticides on hypothalamic-pituitary-gonadal axis: A reproductive health perspective, Environmental Pollution, 10.1016/j.envpol.2018.11.031, 245, (590-599), Online publication date: 1-Feb-2019.Michalíková K, Linhartová L, Ezechiáš M and Cajthaml T (2019) Assessment of agonistic and antagonistic properties of widely used oral care antimicrobial substances toward steroid estrogenic and androgenic receptors, Chemosphere, 10.1016/j.chemosphere.2018.11.006, 217, (534-541), Online publication date: 1-Feb-2019.Kolianchuk Y, Shepelskaya N, Prodanchuk N, Bubalo N and Petrashenko G (2019) THE MODULATING EFFECT OF THE PESTICIDE LAMBDA-CYHALOTHRIN IN THE STUDY OF REPRODUCTIVE TOXICITY IN MALE AND FEMALE WISTAR HAN RATS, Bulletin of Problems Biology and Medicine, 10.29254/2077-4214-2019-3-152-127-131, 3:152, (127), .Cronin M and Yoon M (2019) Computational Methods to Predict Toxicity The History of Alternative Test Methods in Toxicology, 10.1016/B978-0-12-813697-3.00031-7, (287-300), .Kanda R (2019) Reproductive Impact of Environmental Chemicals on Animals Reproductive Sciences in Animal Conservation, 10.1007/978-3-030-23633-5_3, (41-70), .Ockleford C, Adriaanse P, Berny P, Brock T, Duquesne S, Grilli S, Hernandez‐Jerez A, Bennekou S, Klein M, Kuhl T, Laskowski R, Machera K, Pelkonen O, Pieper S, Stemmer M, Sundh I, Teodorovic I, Tiktak A, Topping C, Wolterink G, Aldrich A, Berg C, Ortiz‐Santaliestra M, Weir S, Streissl F and Smith R Scientific Opinion on the state of the science on pesticide risk assessment for amphibians and reptiles, EFSA Journal, 10.2903/j.efsa.2018.5125, 16:2Heise T, Schmidt F, Knebel C, Rieke S, Haider W, Geburek I, Niemann L and Marx-Stoelting P (2017) Hepatotoxic combination effects of three azole fungicides in a broad dose range, Archives of Toxicology, 10.1007/s00204-017-2087-6, 92:2, (859-872), Online publication date: 1-Feb-2018.Westlund P, Isazadeh S and Yargeau V (2018) Investigating the androgenic activity of ozonation transformation products of testosterone and androstenedione, Journal of Hazardous Materials, 10.1016/j.jhazmat.2017.08.032, 342, (492-498), Online publication date: 1-Jan-2018.Popescu M, Sandu C, Rosales E, Pazos M, Lazar G and Sanromán M (2018) Evaluation of different cathodes and reaction parameters on the enhancement of the electro-Fenton process, Journal of Electroanalytical Chemistry, 10.1016/j.jelechem.2017.04.047, 808, (455-463), Online publication date: 1-Jan-2018.Declerck K, Remy S, Wohlfahrt-Veje C, Main K, Van Camp G, Schoeters G, Vanden Berghe W and Andersen H (2017) Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk—an exploratory study, Clinical Epigenetics, 10.1186/s13148-017-0336-4, 9:1, Online publication date: 1-Dec-2017.Westlund P and Yargeau V (2017) Investigation of the presence and endocrine activities of pesticides found in wastewater effluent using yeast-based bioassays, Science of The Total Environment, 10.1016/j.scitotenv.2017.07.032, 607-608, (744-751), Online publication date: 1-Dec-2017.Gaudriault P, Mazaud-Guittot S, Lavoué V, Coiffec I, Lesné L, Dejucq-Rainsford N, Scholze M, Kortenkamp A and Jégou B (2017) Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants, Environmental Health Perspectives, 125:8, Online publication date: 16-Aug-2017.Truter J, van Wyk J, Oberholster P, Botha A and Mokwena L (2016) An evaluation of the endocrine disruptive potential of crude oil water accommodated fractions and crude oil contaminated surface water to freshwater organisms using in vitro and in vivo approaches, Environmental Toxicology and Chemistry, 10.1002/etc.3665, 36:5, (1330-1342), Online publication date: 1-May-2017.Kassotis C, Masse L, Kim S, Schlezinger J, Webster T and Stapleton H (2017) Characterization of Adipogenic Chemicals in Three Different Cell Culture Systems: Implications for Reproducibility Based on Cell Source and Handling, Scientific Reports, 10.1038/srep42104, 7:1Cremonese C, Piccoli C, Pasqualotto F, Clapauch R, Koifman R, Koifman S and Freire C (2017) Occupational exposure to pesticides, reproductive hormone levels and sperm quality in young Brazilian men, Reproductive Toxicology, 10.1016/j.reprotox.2017.01.001, 67, (174-185), Online publication date: 1-Jan-2017.Hamadache M, Amrane A, Benkortbi O, Hanini S, Khaouane L and Si Moussa C (2017) Environmental Toxicity of Pesticides, and Its Modeling by QSAR Approaches Advances in QSAR Modeling, 10.1007/978-3-319-56850-8_13, (471-501), .Pillarisetti J (2016) Skewed sex ratio, environmental toxins and human wellbeing: the need for policies, International Journal of Environmental Studies, 10.1080/00207233.2016.1192387, 73:5, (692-701), Online publication date: 2-Sep-2016.Saillenfait A, Ndiaye D and Sabaté J (2016) The estrogenic and androgenic potential of pyrethroids in vitro. Review, Toxicology in Vitro, 10.1016/j.tiv.2016.02.020, 34, (321-332), Online publication date: 1-Aug-2016.Nappi F, Barrea L, Di Somma C, Savanelli M, Muscogiuri G, Orio F and Savastano S (2016) Endocrine Aspects of Environmental “Obesogen” Pollutants, International Journal of Environmental Research and Public Health, 10.3390/ijerph13080765, 13:8, (765)Tinggaard J, Wohlfahrt‐Veje C, Husby S, Christiansen L, Skakkebæk N, Jensen T, Grandjean P, Main K and Andersen H (2016) Prenatal pesticide exposure and PON1 genotype associated with adolescent body fat distribution evaluated by dual X‐ray absorptiometry (DXA) , Andrology, 10.1111/andr.12194, 4:4, (735-744), Online publication date: 1-Jul-2016.Svartz G, Meijide F and Pérez Coll C (2016) Effects of a fungicide formulation on embryo-larval development, metamorphosis, and gonadogenesis of the South American toad Rhinella arenarum, Environmental Toxicology and Pharmacology, 10.1016/j.etap.2016.05.008, 45, (1-7), Online publication date: 1-Jul-2016.Johansson H, Jacobsen P, Hass U, Svingen T, Vinggaard A, Isling L, Axelstad M, Christiansen S and Boberg J (2016) Perinatal exposure to mixtures of endocrine disrupting chemicals reduces female rat follicle reserves and accelerates reproductive aging, Reproductive Toxicology, 10.1016/j.reprotox.2016.03.045, 61, (186-194), Online publication date: 1-Jun-2016.Ezechiáš M, Janochová J, Filipová A, Křesinová Z and Cajthaml T (2016) Widely used pharmaceuticals present in the environment revealed as in vitro antagonists for human estrogen and androgen receptors, Chemosphere, 10.1016/j.chemosphere.2016.02.067, 152, (284-291), Online publication date: 1-Jun-2016.Hartwig A (2016) ortho-Phenylphenol (OPP) und ortho-Phenylphenol-Natrium (OPP-Na) [MAK Value Documentation in German language, 2016] The MAK-Collection for Occupational Health and Safety, 10.1002/3527600418.mb9043verd0060, (1067-1110)Kugathas S, Audouze K, Ermler S, Orton F, Rosivatz E, Scholze M and Kortenkamp A (2015) Effects of Common Pesticides on Prostaglandin D2 (PGD2) Inhibition in SC5 Mouse Sertoli Cells, Evidence of Binding at the COX-2 Active Site, and Implications for Endocrine Disruption, Environmental Health Perspectives, 124:4, (452-459), Online publication date: 1-Apr-2016.Nassar A, Salim Y and Malhat F (2016) Assessment of Pesticide Residues in Human Blood and Effects of Occupational Exposure on Hematological and Hormonal Qualities, Pakistan Journal of Biological Sciences, 10.3923/pjbs.2016.95.105, 19:3, (95-105), Online publication date: 15-Mar-2016.Truter J, van Wyk J, Oberholster P, Botha A and de Klerk A (2016) An In Vitro and In Vivo Assessment of Endocrine Disruptive Activity in a Major South African River, Water, Air, & Soil Pollution, 10.1007/s11270-016-2748-8, 227:2, Online publication date: 1-Feb-2016.Tournier M, Pouech C, Quignot N, Lafay F, Wiest L, Lemazurier E, Cren-Olivé C and Vulliet E (2015) Determination of endocrine disruptors and endogenic androgens and estrogens in rat serum by high-performance liquid chromatography–tandem mass spectrometry, Steroids, 10.1016/j.steroids.2015.10.011, 104, (252-262), Online publication date: 1-Dec-2015.Hamers T, Kamstra J, van Gils J, Kotte M and van Hattum A (2015) The influence of extreme river discharge conditions on the quality of suspended particulate matter in Rivers Meuse and Rhine (The Netherlands), Environmental Research, 10.1016/j.envres.2015.10.019, 143, (241-255), Online publication date: 1-Nov-2015.Yaglova N and Yaglov V (2015) Altered thyroid hormone production induced by long-term exposure to low doses of the endocrine disruptor dichlorodiphenyltrichloroethane, Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 10.1134/S1990750815040083, 9:4, (339-342), Online publication date: 1-Oct-2015.Kassotis C, Alvarez D, Taylor J, vom Saal F, Nagel S and Tillitt D (2015) Characterization of Missouri surface waters near point sources of pollution reveals potential novel atmospheric route of exposure for bisphenol A and wastewater hormonal activity pattern, Science of The Total Environment, 10.1016/j.scitotenv.2015.04.013, 524-525, (384-393), Online publication date: 1-Aug-2015.Nieradko-Iwanicka B and Borzęcki A (2015) Subacute poisoning of mice with deltamethrin produces memory impairment, reduced locomotor activity, liver damage and changes in blood morphology in the mechanism of oxidative stress, Pharmacological Reports, 10.1016/j.pharep.2014.12.012, 67:3, (535-541), Online publication date: 1-Jun-2015.Dantas T, Cancian G, Neodini D, Mano D, Capucho C, Predes F, Pulz R, Pigoso A, Dolder H and Severi-Aguiar G (2015) Leydig cell number and sperm production decrease induced by chronic ametryn exposure: a negative impact on animal reproductive health, Environmental Science and Pollution Research, 10.1007/s11356-014-4010-5, 22:11, (8526-8535), Online publication date: 1-Jun-2015.Gil F, Moreira-Santos M, Chelinho S, Pereira C, Feliciano J, Leitão J, Sousa J, Ribeiro R and Viegas C (2015) Suitability of a Saccharomyces cerevisiae-based assay to assess the toxicity of pyrimethanil sprayed soils via surface runoff: Comparison with standard aquatic and soil toxicity assays, Science of The Total Environment, 10.1016/j.scitotenv.2014.09.094, 505, (161-171), Online publication date: 1-Feb-2015.Andersen H, Debes F, Wohlfahrt-Veje C, Murata K and Grandjean P (2015) Occupational pesticide exposure in early pregnancy associated with sex-specific neurobehavioral deficits in the children at school age, Neurotoxicology and Teratology, 10.1016/j.ntt.2014.10.006, 47, (1-9), Online publication date: 1-Jan-2015.Yaglova N and Yaglov V (2014) Alteration of thyroid hormone secretion after long-term exposure to low doses of endocrine disruptor DDT, Biomeditsinskaya Khimiya, 10.18097/PBMC20146006655, 60:6, (655-660), Online publication date: 1-Nov-2014.Blazer V, Iwanowicz D, Walsh H, Sperry A, Iwanowicz L, Alvarez D, Brightbill R, Smith G, Foreman W and Manning R (2014) Reproductive health indicators of fishes from Pennsylvania watersheds: association with chemicals of emerging concern, Environmental Monitoring and Assessment, 10.1007/s10661-014-3868-5, 186:10, (6471-6491), Online publication date: 1-Oct-2014.Sébillot A, Damdimopoulou P, Ogino Y, Spirhanzlova P, Miyagawa S, Du Pasquier D, Mouatassim N, Iguchi T, Lemkine G, Demeneix B and Tindall A (2014) Rapid Fluorescent Detection of (Anti)androgens with spiggin-gfp Medaka , Environmental Science & Technology, 10.1021/es5030977, 48:18, (10919-10928), Online publication date: 16-Sep-2014.Juul A, Almstrup K, Andersson A, Jensen T, Jørgensen N, Main K, Meyts E, Toppari J and Skakkebæk N (2014) Possible fetal determinants of male infertility, Nature Reviews Endocrinology, 10.1038/nrendo.2014.97, 10:9, (553-562), Online publication date: 1-Sep-2014.Christen V, Crettaz P and Fent K (2014) Additive and synergistic antiandrogenic activities of mixtures of azol fungicides and vinclozolin, Toxicology and Applied Pharmacology, 10.1016/j.taap.2014.06.025, 279:3, (455-466), Online publication date: 1-Sep-2014.Tago D, Andersson H and Treich N (2014) Pesticides and Health: A Review of Evidence on Health Effects, Valuation of Risks, and Benefit-Cost Analysis Preference Measurement in Health, 10.1108/S0731-219920140000024006, (203-295), Online publication date: 27-Aug-2014.Orton F, Ermler S, Kugathas S, Rosivatz E, Scholze M and Kortenkamp A (2014) Mixture effects at very low doses with combinations of anti-androgenic pesticides, antioxidants, industrial pollutant and chemicals used in personal care products, Toxicology and Applied Pharmacology, 10.1016/j.taap.2013.09.008, 278:3, (201-208), Online publication date: 1-Aug-2014.Gil F, Becker J and Viegas C (2014) Potential Mechanisms Underlying Response to Effects of the Fungicide Pyrimethanil from Gene Expression Profiling in Saccharomyces cerevisiae , Journal of Agricultural and Food Chemistry, 10.1021/jf5007775, 62:23, (5237-5247), Online publication date: 11-Jun-2014.(2014) Anti‐Androgenic Chemicals Endocrine Disruptors in the Environment, 10.1002/9781118891094.ch4, (91-110), Online publication date: 9-Jun-2014.Regnier S and Sargis R (2014) Adipocytes under assault: Environmental disruption of adipose physiology, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 10.1016/j.bbadis.2013.05.028, 1842:3, (520-533), Online publication date: 1-Mar-2014.Wolf C, Rider C, Lau C and Abbott B (2014) Evaluating the additivity of perfluoroalkyl acids in binary combinations on peroxisome proliferator-activated receptor-α activation, Toxicology, 10.1016/j.tox.2013.12.002, 316, (43-54), Online publication date: 1-Feb-2014.Passananti M, Lavorgna M, Iesce M, DellaGreca M, Criscuolo E, Parrella A, Isidori M and Temussi F (2014) Chlorpropham and phenisopham: phototransformation and ecotoxicity of carbamates in the aquatic environment, Environ. Sci.: Processes Impacts, 10.1039/C3EM00400G, 16:4, (823-831)Long M, Strand J, Lassen P, Krüger T, Dahllöf I, Bossi R, Larsen M, Wiberg-Larsen P and Bonefeld-Jørgensen E (2013) Endocrine-Disrupting Effects of Compounds in Danish Streams, Archives of Environmental Contamination and Toxicology, 10.1007/s00244-013-9959-4, 66:1, (1-18), Online publication date: 1-Jan-2014.Schiller V, Wichmann A, Kriehuber R, Schäfers C, Fischer R and Fenske M (2013) Transcriptome alterations in zebrafish embryos after exposure to environmental estrogens and anti-androgens can reveal endocrine disruption, Reproductive Toxicology, 10.1016/j.reprotox.2013.09.003, 42, (210-223), Online publication date: 1-Dec-2013.Taxvig C, Hadrup N, Boberg J, Axelstad M, Bossi R, Bonefeld-Jørgensen E and Vinggaard A (2013) In vitro - in vivo correlations for endocrine activity of a mixture of currently used pesticides, Toxicology and Applied Pharmacology, 10.1016/j.taap.2013.07.028, 272:3, (757-766), Online publication date: 1-Nov-2013.Bailey K and Fry R (2013) Environmental Toxicants and Perturbation of miRNA Signaling microRNAs in Toxicology and Medicine, 10.1002/9781118695999.ch2, (5-31), Online publication date: 7-Oct-2013.Pan C, Wang Q, Liu Y, Xu L, Li Y, Hu J, Jiang M, Zhang J, Zhang M, Yu H, Zhou J, Zhou X and Xu L (2013) Anti-androgen effects of the pyrethroid pesticide cypermethrin on interactions of androgen receptor with corepressors, Toxicology, 10.1016/j.tox.2013.06.011, 311:3, (178-183), Online publication date: 1-Sep-2013.Pottinger T, Katsiadaki I, Jolly C, Sanders M, Mayer I, Scott A, Morris S, Kortenkamp A and Scholze M (2013) Anti-androgens act jointly in suppressing spiggin concentrations in androgen-primed female three-spined sticklebacks – Prediction of combined effects by concentration addition, Aquatic Toxicology, 10.1016/j.aquatox.2013.05.020, 140-141, (145-156), Online publication date: 1-Sep-2013.Hu X, Shi W, Wei S, Zhang X, Feng J, Hu G, Chen S, Giesy J and Yu H (2013) Occurrence and Potential Causes of Androgenic Activities in Source and Drinking Water in China, Environmental Science & Technology, 10.1021/es401464p, (130828135947000)Overgaard A, Holst K, Mandrup K, Boberg J, Christiansen S, Jacobsen P, Hass U and Mikkelsen J (2013) The effect of perinatal exposure to ethinyl oestradiol or a mixture of endocrine disrupting pesticides on kisspeptin neurons in the rat hypothalamus, NeuroToxicology, 10.1016/j.neuro.2013.04.012, 37, (154-162), Online publication date: 1-Jul-2013.Valeri C, Schteingart H and Rey R (2013) The prepubertal testis, Current Opinion in Endocrinology, Diabetes & Obesity, 10.1097/MED.0b013e328360be2c, 20:3, (224-233), Online publication date: 1-Jun-2013.Wang X, Li X, Shi W, Wei S, Giesy J, Yu H and Wang Y (2013) Docking and CoMSIA studies on steroids and non-steroidal chemicals as androgen receptor ligands, Ecotoxicology and Environmental Safety, 10.1016/j.ecoenv.2012.11.020, 89, (143-149), Online publication date: 1-Mar-2013.Teng Y, Manavalan T, Hu C, Medjakovic S, Jungbauer A and Klinge C (2012) Endocrine Disruptors Fludioxonil and Fenhexamid Stimulate miR-21 Expression in Breast Cancer Cells, Toxicological Sciences, 10.1093/toxsci/kfs290, 131:1, (71-83), Online publication date: 1-Jan-2013., Online publication date: 1-Jan-2013.Lorenzetti* S and Narciso L (2012) Nuclear Receptors: Connecting Human Health to the Environment Computational Approaches to Nuclear Receptors, 10.1039/9781849735353-00001, (1-22)Orton F, Rosivatz E, Scholze M and Kortenkamp A (2012) Competitive Androgen Receptor Antagonism as a Factor Determining the Predictability of Cumulative Antiandrogenic Effects of Widely Used Pesticides, Environmental Health Perspectives, 120:11, (1578-1584), Online publication date: 1-Nov-2012.Reilly T, Smalling K, Orlando J and Kuivila K (2012) Occurrence of boscalid and other selected fungicides in surface water and groundwater in three targeted use areas in the United States, Chemosphere, 10.1016/j.chemosphere.2012.04.023, 89:3, (228-234), Online publication date: 1-Sep-2012.Andersen H, Wohlfahrt-Veje C, Dalgård C, Christiansen L, Main K, Nellemann C, Murata K, Jensen T, Skakkebæk N, Grandjean P and Amre D (2012) Paraoxonase 1 Polymorphism and Prenatal Pesticide Exposure Associated with Adverse Cardiovascular Risk Profiles at School Age, PLoS ONE, 10.1371/journal.pone.0036830, 7:5, (e36830)Hu J, Li Y, Pan C, Zhang J, Wang H, Li J and Xu L (2012) Anti-androgen effects of cypermethrin on the amino- and carboxyl-terminal interaction of the androgen receptor, Toxicology, 10.1016/j.tox.2011.11.019, 292:2-3, (99-104), Online publication date: 1-Feb-2012.De Coster S and van Larebeke N (2012) Endocrine-Disrupting Chemicals: Associated Disorders and Mechanisms of Action, Journal of Environmental and Public Health, 10.1155/2012/713696, 2012, (1-52), .Wohlfahrt-Veje C, Main K, Schmidt I, Boas M, Jensen T, Grandjean P, Skakkebæk N and Andersen H (2011) Lower birth weight and increased body fat at school age in children prenatally exposed to modern pesticides: a prospective study, Environmental Health, 10.1186/1476-069X-10-79, 10:1, Online publication date: 1-Dec-2011.
Publication History
- Manuscript received25 August 2010
- Manuscript accepted10 February 2011
- Originally published10 February 2011
- Published in print1 June 2011
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