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2016 Conference

Abstract Number: E-03 | ID: 4180

Birth cohort consortium of Asia (BiCCA) and new big national cohorts: why are they functioning in Asia?  Pros and Cons of small and large one

Reiko kishi*, hokkaido University, Japan,;
Proposed Symposium Title: The end of big birth cohorts
Chair and co-chair names and institutions: Manolis Kogevinas, CREAL, Barcelona and Brenda Eskenazi, Berkeley, CA, USA
ASIA contains half of the world's children, and the countries of Asia are the most rapidly industrializing nations of the globe. Environmental threats to the health of children are myriad in Asia. The prevalence of environmentally related diseases such as allergic disease, obesity, and ADHD & autism is increasing dramatically in Asia. PI of the Hokkaido Study on Environment and Children' Health (Hokkaido Study), Japan, the Mothers and Children's Environmental Health Study (MOCEH), Korea and Taiwan Birth Panel Study (TBPS) co-established Birth Cohort Consortium of Asia (BiCCA) in 2011. Until up to now, 23 cohorts in 10 Asian countries (China, Japan, Korea, Malaysia, Nepal, Philippines, Singapore, Sri Lanka, Taiwan, Vietnam), summed up 75,000 study subjects are joining BiCCA. The Japan environment and children’s study (JECS) cohort launched recruiting from 2011, and it had ca.100, 000 mothers/children pairs’ records in 2014. Another large scale of Korean national cohort has started their enrollment since 2015. Our experiences based on both small (n=514) and large (n=20,929) scale Hokkaido cohort, which was one of the models of the national study JECS, indicate that each cohort has significant original existence because in a smaller cohort new novel hypotheses or trials are easily verifiable. On the other hand, in larger national cohorts, the etiology of rare diseases such as congenital malformation could be analysed, but they need huge amount of cost and human resources. The main strength of the Asian studies including some overcoming challenges would be referred in the symposium. For the future harmonization, further scientific cooperation should be stressed not only in Asia but also in the world.