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Environmental Health Perspectives

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July 2012 | Volume 120 | Issue 7

News


Focus

 

EHP120N7_July2012_smallThe Future of Fracking: New Rules Target Air Emissions for Cleaner Natural Gas Production

Bob Weinhold
A272–A279 | http://dx.doi.org/10.1289/ehp.120-A272

Natural gas is lauded as a cleaner-burning fuel than either coal or oil, but getting the fuel out of the ground can be a dirty process, especially given the widespread adoption of the technology known as hydraulic fracturing (“fracking”). Concerns about toxic air emissions from previously unregulated fracking sites led to the U.S. Environmental Protection Agency announcement on 18 April 2012 of new and updated air pollution regulations for these facilities and certain other elements of oil and natural gas production and transmission. Compliance with the new regulations is expected to result in major reductions in emissions of methane and volatile organic compounds, particularly from new fracked natural gas wells.

Forum

 

CDC Updates Guidelines for Children’s Lead Exposure

 

Maryland Bans Arsenical Drug in Chicken Feed

Charles W. Schmidt
A269 | http://dx.doi.org/10.1289/ehp.120-A269

 

Newly Discovered Mechanism for Chlorpyrifos Effects on Neurodevelopment

Carol Potera
A270–A271 | http://dx.doi.org/10.1289/ehp.120-A270a

 

The Beat

Erin E. Dooley
A270–A271 | http://dx.doi.org/10.1289/ehp.120-A270b

Spheres of Influence

 

Spheres_TOCWhy Is It So Difficult to Choose Safer Alternatives for Hazardous Chemicals?

Valerie J. Brown
A280–A283 | http://dx.doi.org/10.1289/ehp.120-A280

The discovery of persistent, bioaccumulative, and toxic flame-retardant chemicals everywhere from animals north of the Arctic Circle to the breast milk of California women has been a cause for considerable concern. Alternative flame retardants were introduced to replace these chemicals, but investigators had not even produced the first empirical data on the substitutes’ metabolic fate and toxicity before emerging evidence indicated they, like their predecessors, were accumulating rapidly in the environment. As the postmarket research continues, one wonders: Who, exactly, decides on the replacements for toxic chemicals, and on the basis of what criteria? And why does finding truly safer alternatives seem so difficult?

 

Science Selections

 

Housekeeping Tip: Long-Term Frequent Use of Some Household Products May Affect Heart Rate Variability

Julia R. Barrett
A284 | http://dx.doi.org/10.1289/ehp.120-A284a

 

Glow Fish: A New Biosensor to Detect How Environmental Estrogens Affect Tissues

 

Judging the Data: Peer Review versus Good Laboratory Practice Standards

Charles W. Schmidt
A285 | http://dx.doi.org/10.1289/ehp.120-A285a

 

A Sensitive Approach to Studying ASDs: Teasing Out Relationships between Autism and Maternal Smoking

 

Reviews


 

Information Quality in Regulatory Decision Making: Peer Review versus Good Laboratory Practice

Lynn S. McCarty, Christopher J. Borgert, Ellen M. Mihaich
927–934 | http://dx.doi.org/10.1289/ehp.1104277

 

Endocrine Disruptors and Asthma-Associated Chemicals in Consumer Products

Robin E. Dodson, Marcia Nishioka, Laurel J. Standley, Laura J. Perovich, Julia Green Brody, Ruthann A. Rudel
935–943 | http://dx.doi.org/10.1289/ehp.1104052

 

Tipping the Balance of Autism Risk: Potential Mechanisms Linking Pesticides and Autism

Janie F. Shelton, Irva Hertz-Picciotto, Isaac N. Pessah
944–951 | http://dx.doi.org/10.1289/ehp.1104553

Research


 

Omega-3 Fatty Acid Supplementation Appears to Attenuate Particulate Air Pollution–Induced Cardiac Effects and Lipid Changes in Healthy Middle-Aged Adults

Haiyan Tong, Ana G Rappold, David Diaz-Sanchez, Susan E Steck, Jon Berntsen, Wayne E Cascio, Robert B Devlin, James M Samet
952–957 | http://dx.doi.org/10.1289/ehp.1104472

 

Heart Rate Variability in Association with Frequent Use of Household Sprays and Scented Products in SAPALDIA

Amar J. Mehta, Martin Adam, Emmanuel Schaffner, Jean-Claude Barthélémy, David Carballo, Jean-Michel Gaspoz, Thierry Rochat, Christian Schindler, Joel Schwartz, Jan-Paul Zock, Nino Künzli, Nicole Probst-Hensch, SAPALDIA Team
958–964 | http://dx.doi.org/10.1289/ehp.1104567

 

Chronic Exposure to Fine Particles and Mortality: An Extended Follow-up of the Harvard Six Cities Study from 1974 to 2009

Johanna Lepeule, Francine Laden, Douglas Dockery, Joel Schwartz
965–970 | http://dx.doi.org/10.1289/ehp.1104660

 

Neighborhood Built Environment and Transport and Leisure Physical Activity: Findings Using Objective Exposure and Outcome Measures in New Zealand

Karen Witten, Tony Blakely, Nasser Bagheri, Hannah Badland, Vivienne Ivory, Jamie Pearce, Suzanne Mavoa, Erica Hinckson, Grant Schofield
971–977 | http://dx.doi.org/10.1289/ehp.1104584

 

Urinary Bisphenol A Concentrations and Implantation Failure among Women Undergoing in Vitro Fertilization

Shelley Ehrlich, Paige L. Williams, Stacey A. Missmer, Jodi A. Flaws, Katharine F. Berry, Antonia M. Calafat, Xiaoyun Ye, John C. Petrozza, Diane Wright, Russ Hauser
978–983 | http://dx.doi.org/10.1289/ehp.1104307

 

Bisphenol A Diglycidyl Ether Induces Adipogenic Differentiation of Multipotent Stromal Stem Cells through a Peroxisome Proliferator–Activated Receptor Gamma-Independent Mechanism

Raquel Chamorro-García, Séverine Kirchner, Xia Li, Amanda Janesick, Stephanie C. Casey, Connie Chow, Bruce Blumberg
984–989 | http://dx.doi.org/10.1289/ehp.1205063

 

Biosensor Zebrafish Provide New Insights into Potential Health Effects of Environmental Estrogens

Okhyun Lee, Aya Takesono, Masazumi Tada, Charles R. Tyler, Tetsuhiro Kudoh
990–996 | http://dx.doi.org/10.1289/ehp.1104433

 

PCB-95 Promotes Dendritic Growth via Ryanodine Receptor–Dependent Mechanisms

Gary A. Wayman, Dongren Yang, Diptiman D. Bose, Adam Lesiak, Veronica Ledoux, Donald Bruun, Isaac N. Pessah, Pamela J. Lein
997–1002 | http://dx.doi.org/10.1289/ehp.1104832

 

PCB-95 Modulates the Calcium-Dependent Signaling Pathway Responsible for Activity-Dependent Dendritic Growth

Gary A. Wayman, Diptiman D. Bose, Dongren Yang, Adam Lesiak, Donald Bruun, Soren Impey, Veronica Ledoux, Isaac N. Pessah, Pamela J. Lein
1003–1009 | http://dx.doi.org/10.1289/ehp.1104833

 

Exposure to Secondhand Smoke Outside of a Bar and a Restaurant and Tobacco Exposure Biomarkers in Nonsmokers

Gideon St.Helen, J. Thomas Bernert, Daniel B. Hall, Connie S. Sosnoff, Yang Xia, John R. Balmes, John E. Vena, Jia-Sheng Wang, Nina T. Holland, Luke P. Naeher
1010–1016 | http://dx.doi.org/10.1289/ehp.1104413

 

Cadmium Exposure and All-Cause and Cardiovascular Mortality in the U.S. General Population

Maria Tellez-Plaza, Ana Navas-Acien, Andy Menke, Ciprian M. Crainiceanu, Roberto Pastor-Barriuso, Eliseo Guallar
1017–1022 | http://dx.doi.org/10.1289/ehp.1104352

 

Air Pollution and Symptoms of Depression in Elderly Adults

Youn-Hee Lim, Ho Kim, Jin Hee Kim, Sanghyuk Bae, Hye Yin Park, Yun-Chul Hong
1023–1028 | http://dx.doi.org/10.1289/ehp.1104100

 

Differential Estrogenic Actions of Endocrine-Disrupting Chemicals Bisphenol A, Bisphenol AF, and Zearalenone through Estrogen Receptor α and β in Vitro

Yin Li, Katherine A. Burns, Yukitomo Arao, Colin J. Luh, Kenneth S. Korach
1029–1035 | http://dx.doi.org/10.1289/ehp.1104689

Children’s Health

 

Thyroid Function and Perfluoroalkyl Acids in Children Living Near a Chemical Plant

Maria-Jose Lopez-Espinosa, Debapriya Mondal, Ben Armstrong, Michael S. Bloom, Tony Fletcher
1036–1041 | http://dx.doi.org/10.1289/ehp.1104370

 

Maternal Smoking during Pregnancy and the Prevalence of Autism Spectrum Disorders, Using Data from the Autism and Developmental Disabilities Monitoring Network

Amy E. Kalkbrenner, Joe M. Braun, Maureen S. Durkin, Matthew J. Maenner, Christopher Cunniff, Li-Ching Lee, Sydney Pettygrove, Joyce S. Nicholas, Julie L. Daniels
1042–1048 | http://dx.doi.org/10.1289/ehp.1104556

 

Serum PBDEs in a North Carolina Toddler Cohort: Associations with Handwipes, House Dust, and Socioeconomic Variables

Heather M. Stapleton, Sarah Eagle, Andreas Sjödin, Thomas F. Webster
1049–1054 | http://dx.doi.org/10.1289/ehp.1104802

 

Associations of Prenatal Exposure to Organophosphate Pesticide Metabolites with Gestational Age and Birth Weight

Stephen A. Rauch, Joe M. Braun, Dana Boyd Barr, Antonia M. Calafat, Jane Khoury, M. Angela Montesano, Kimberly Yolton, Bruce P. Lanphear
1055–1060 | http://dx.doi.org/10.1289/ehp.1104615

 

Prenatal Arsenic Exposure and DNA Methylation in Maternal and Umbilical Cord Blood Leukocytes

Molly L. Kile, Andrea Baccarelli, Elaine Hoffman, Letizia Tarantini, Quazi Quamruzzaman, Mahmuder Rahman, Golam Mahiuddin, Golam Mostofa, Yu-Mei Hsueh, Robert O. Wright, David C. Christiani
1061–1066 | http://dx.doi.org/10.1289/ehp.1104173

 

Perspectives


Editorials

 

A Research Strategy to Discover the Environmental Causes of Autism and Neurodevelopmental Disabilities

Philip J. Landrigan, Luca Lambertini, Linda S. Birnbaum
A258–A260 | http://dx.doi.org/10.1289/ehp.1104285

 

Measuring Partnership Activities: Partnerships in Environmental Public Health Evaluation Metrics Manual

Christina H. Drew, Kristianna G. Pettibone, Liam R. O’Fallon, Gwen W. Collman, Linda S. Birnbaum
A261–A262 | http://dx.doi.org/10.1289/ehp.1205512

 

EHP Classic Paper of the Year, 2012

Podcast

 

What Do We Know about Obesogens? with Bruce Blumberg

Correspondence

 

Approaches to Human Health Risk Assessment Based on the Signal-To-Noise Crossover Dose

Weihsueh A. Chiu, Kathryn Z. Guyton, Karen Hogan, Jennifer Jinot
A264 | http://dx.doi.org/10.1289/ehp.1205212

 

Signal-To-Noise Crossover Dose: Sand et al. Respond

Salomon Sand, Christopher J. Portier, Daniel Krewski
A264–A265 | http://dx.doi.org/10.1289/ehp.1205212R

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