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Environmental Health Perspectives

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October 2013 | Volume 121 | Issue 10



Uncertain Inheritance: Transgenerational Effects of Environmental Exposures

October 2013 cover

Charles W. Schmidt | A298

Animal studies have reported transgenerational effects for chemicals including permethrin, DEET, bisphenol A, a number of phthalates, dioxin, jet fuel mixtures, nicotine, and tributyltin, among others. Although no human data yet exist for effects to the F3 generation, several studies have documented multigenerational chemical impacts, and the new findings are spurring a reevaluation of how scientists perceive environmental health threats.



Spheres of Influence

The Minamata Convention on Mercury: A First Step toward Protecting Future Generations

Minamata disease patient with doctor

Rebecca Kessler | A304

The Minamata disaster was the first large-scale incident of methylmercury poisoning, and it drew the world’s attention to the devastating effects of this powerful neurotoxicant, now known to be particularly dangerous to fetuses, infants, and young children. In October 2013 a new convention to control mercury emissions opens for signing in Japan in recognition of the fact that mercury pollution is a global problem no one country can solve alone.



Science Selections

A New Breed of Model: Estimating the Impact of Climate Change on Malaria Transmission

Claudia M. Caruana | A310

Also see Yamana and Eltahir, p. 1179

Prenatal Protection: Maternal Diet May Modify Impact of PAHs

Julia R. Barrett | A311

Also see Pedersen et al., p. 1200

Arsenic Handicap? Prenatal Exposure Worsens Influenza Infections in Young Mice

Carol Potera | A312

Also see Ramsey et al., p. 1187

Molecular Competition: Flame Retardants Interact with Key Metabolism Enzyme

Kellyn S. Betts | A313

Also see Gosavi et al., p. 1194


Methods to Calculate the Heat Index as an Exposure Metric in Environmental Health Research

G. Brooke Anderson, Michelle L. Bell, and Roger D. Peng | 1111

Health and Household Air Pollution from Solid Fuel Use: The Need for Improved Exposure Assessment

Maggie L. Clark, Jennifer L. Peel, Kalpana Balakrishnan, Patrick N. Breysse, Steven N. Chillrud, Luke P. Naeher, Charles E. Rodes, Alan F. Vette, and John M. Balbus | 1120


Phthalate Exposure and Allergy in the U.S. Population: Results from NHANES 2005–2006

Jane A. Hoppin, Renee Jaramillo, Stephanie J. London, Randi J. Bertelsen, Päivi M. Salo, Dale P. Sandler, and Darryl C. Zeldin | 1129

Particulate Air Pollution, Ambulatory Heart Rate Variability, and Cardiac Arrhythmia in Retirement Community Residents with Coronary Artery Disease

Scott M. Bartell, John Longhurst, Thomas Tjoa, Constantinos Sioutas, and Ralph J. Delfino | 1135

Evaluation of a Wildfire Smoke Forecasting System as a Tool for Public Health Protection

Jiayun Yao, Michael Brauer, and Sarah B. Henderson | 1142

Short-term Exposure to Particulate Matter Constituents and Mortality in a National Study of U.S. Urban Communities

Jenna R. Krall, G. Brooke Anderson, Francesca Dominici, Michelle L. Bell, and Roger D. Peng | 1148

A Population-based Case–Control Study of Urinary Arsenic Species and Squamous Cell Carcinoma in New Hampshire, USA

Diane Gilbert-Diamond, Zhigang Li, Ann E. Perry, Steven K. Spencer, A. Jay Gandolfi, and Margaret R. Karagas | 1154

Evaluating Nanoparticle Breakthrough during Drinking Water Treatment

Talia E. Abbott Chalew, Gaurav S. Ajmani, Haiou Huang, and Kellogg J. Schwab | 1161

Urinary Glycol Ether Metabolites in Women and Time to Pregnancy: The PELAGIE Cohort

Ronan Garlantézec, Charline Warembourg, Christine Monfort, Laurence Labat, Juha Pulkkinen, Nathalie Bonvallot, Luc Multigner, Cécile Chevrier, and Sylvaine Cordier | 1167

Size-Fractionated Particle Number Concentrations and Daily Mortality in a Chinese City

Xia Meng, Yanjun Ma, Renjie Chen, Zhijun Zhou, Bingheng Chen, and Haidong Kan | 1174

Projected Impacts of Climate Change on Environmental Suitability for Malaria Transmission in West Africa

Teresa K. Yamana and Elfatih A.B. Eltahir | 1179

Also see Science Selections, p. A310

Early Life Arsenic Exposure and Acute and Long-term Responses to Influenza A Infection in Mice

Kathryn A. Ramsey, Rachel E. Foong, Peter D. Sly, Alexander N. Larcombe, and Graeme R. Zosky | 1187

Also see Science Selections, p. A312

Mimicking of Estradiol Binding by Flame Retardants and Their Metabolites: A Crystallographic Analysis

Rajendrakumar A. Gosavi, Gabriel A. Knudsen, Linda S. Birnbaum, and Lars C. Pedersen | 1194

Also see Science Selections, p. A313

Children’s Health

Bulky DNA Adducts in Cord Blood, Maternal Fruit-and-Vegetable Consumption, and Birth Weight in a European Mother–Child Study (NewGeneris)

Marie Pedersen, Bernadette Schoket, Roger W. Godschalk, John Wright, Hans von Stedingk, Margareta Törnqvist, Jordi Sunyer, Jeanette K. Nielsen, Domenico F. Merlo, Michelle A. Mendez, Helle M. Meltzer, Viktória Lukács, Anette Landström, Soterios A. Kyrtopoulos, Katalin Kovács, Lisbeth E. Knudsen, Margaretha Haugen, Laura J. Hardie, Kristine B. Gützkow, Sarah Fleming, Eleni Fthenou, Peter B. Farmer, Aina Espinosa, Leda Chatzi, Gunnar Brunborg, Nigel J. Brady, Maria Botsivali, Khelifa Arab, Lívia Anna, Jan Alexander, Silvia Agramunt, Jos C. Kleinjans, Dan Segerbäck, and Manolis Kogevinas | 1200

Also see Science Selections, p. A311

Serum Perfluorooctanoic Acid and Perfluorooctane Sulfonate Concentrations in Relation to Birth Outcomes in the Mid-Ohio Valley, 2005–2010

Lyndsey A. Darrow, Cheryl R. Stein, and Kyle Steenland | 1207

Dietary Predictors of Maternal Prenatal Blood Mercury Levels in the ALSPAC Birth Cohort Study

Jean Golding, Colin D. Steer, Joseph R. Hibbeln, Pauline M. Emmett, Tony Lowery, and Robert Jones | 1214

Is the Relationship between Prenatal Exposure to PCB-153 and Decreased Birth Weight Attributable to Pharmacokinetics?

Marc-André Verner, Robin McDougall, Anders Glynn, Melvin E. Andersen, Harvey J. Clewell III, and Matthew P. Longnecker | 1219

Prenatal Exposure to Environmental Phenols: Concentrations in Amniotic Fluid and Variability in Urinary Concentrations during Pregnancy

Claire Philippat, Mary S. Wolff, Antonia M. Calafat, Xiaoyun Ye, Rebecca Bausell, Molly Meadows, Joanne Stone, Rémy Slama, and Stephanie M. Engel  | 1225

Long-term Exposure to PM10 and NO2 in Association with Lung Volume and Airway Resistance in the MAAS Birth Cohort

Anna Mölter, Raymond M. Agius, Frank de Vocht, Sarah Lindley, William Gerrard, Lesley Lowe, Danielle Belgrave, Adnan Custovic, and Angela Simpson | 1232

Domestic Radon Exposure and Risk of Childhood Cancer: A Prospective Census-Based Cohort Study

Dimitri Hauri, Ben Spycher, Anke Huss, Frank Zimmermann, Michael Grotzer, Nicolas von der Weid, Damien Weber, Adrian Spoerri, Claudia E. Kuehni, and Martin Röösli, for the Swiss National Cohort and the Swiss Paediatric Oncology Group (SPOG) | 1239



Shale Gas Extraction in North Carolina: Research Recommendations and Public Health Implications

Adrian Down, Martin Armes, and Robert B. Jackson | A292

Childhood Lead Poisoning in China: Challenges and Opportunities

Chong-huai Yan, Jian Xu, and Xiao-ming Shen | A294


Urinary Cadmium as a Marker of Exposure in Epidemiological Studies

Scott V. Adams and Polly A. Newcomb | A296

Urinary Cadmium as a Marker of Exposure in Epidemiological Studies: Bernard and Chaumont Respond

Alfred Bernard and Agnès Chaumont | A296

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