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Environmental Health Perspectives

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January 2016 | Volume 124 | Issue 1

Editorial


NIEHS Celebrates 50 Years of Environmental Health Research at the NIH

Linda S. Birnbaum

Perspectives on the Children’s Health Collection 2015

Sally Perreault Darney and Martha M. Dimes

Renewing the Federal Commitment to Advance Children’s Health: The President’s Task Force on Environmental Health Risks and Safety Risks to Children

Ruth A. Etzel and Sandra N. Howard

Focus


A Scourge Returns: Black Lung in Appalachia

Carrie Arnold

Spheres of Influence


Beyond a One-Time Scandal: Europe’s Ongoing Diesel Pollution Problem

Charles W. Schmidt

Science Selection


Weeding Out Risk Factors? Study Reports No Association between Prenatal Air Pollution and Autism

Wendee Nicole

Brief Communication


What Can Epidemiological Studies Tell Us about the Impact of Chemical Mixtures on Human Health?

Joseph M. Braun, Chris Gennings, Russ Hauser, and Thomas F. Webster

Commentary


Confusion about Cadmium Risks: The Unrecognized Limitations of an Extrapolated Paradigm

Alfred Bernard

Evidence from Toxicology: The Most Essential Science for Prevention

Daniele Mandrioli and Ellen Kovner Silbergeld

Review


Global Association of Cold Spells and Adverse Health Effects: A Systematic Review and Meta-Analysis

Niilo R.I. Ryti, Yuming Guo, and Jouni J.K. Jaakkola

Research


Long-term PM2.5 Exposure and Neurological Hospital Admissions in the Northeastern United States

Marianthi-Anna Kioumourtzoglou, Joel D. Schwartz, Marc G. Weisskopf, Steven J. Melly, Yun Wang, Francesca Dominici, and Antonella Zanobetti

Vehicular Traffic–Related Polycyclic Aromatic Hydrocarbon Exposure and Breast Cancer Incidence: The Long Island Breast Cancer Study Project (LIBCSP)

Irina Mordukhovich, Jan Beyea, Amy H. Herring, Maureen Hatch, Steven D. Stellman, Susan L. Teitelbaum, David B. Richardson, Robert C. Millikan, Lawrence S. Engel, Sumitra Shantakumar, Susan E. Steck, Alfred I. Neugut, Pavel Rossner Jr., Regina M. Santella, and Marilie D. Gammon

Paired Serum and Urine Concentrations of Biomarkers of Diethyl Phthalate, Methyl Paraben, and Triclosan in Rats

Susan L. Teitelbaum, Qian Li, Luca Lambertini, Fiorella Belpoggi, Fabiana Manservisi, Laura Falcioni, Luciano Bua, Manori J. Silva, Xiaoyun Ye, Antonia M. Calafat, and Jia Chen

Low-Concentration PM2.5 and Mortality: Estimating Acute and Chronic Effects in a Population-Based Study

Liuhua Shi, Antonella Zanobetti, Itai Kloog, Brent A. Coull, Petros Koutrakis, Steven J. Melly, and Joel D. Schwartz

A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways

Martin B. Phillips, Jeremy A. Leonard, Christopher M. Grulke, Daniel T. Chang, Stephen W. Edwards, Raina Brooks, Michael-Rock Goldsmith, Hisham El-Masri, and Yu-Mei Tan

Different ATM Signaling in Response to Chromium(VI) Metabolism via Ascorbate and Nonascorbate Reduction: Implications for in Vitro Models and Toxicogenomics

Michal W. Luczak, Samantha E. Green, and Anatoly Zhitkovich

Smoking-Associated DNA Methylation Biomarkers and Their Predictive Value for All-Cause and Cardiovascular Mortality

Yan Zhang, Ben Schöttker, Ines Florath, Christian Stock, Katja Butterbach, Bernd Holleczek, Ute Mons, and Hermann Brenner

Suicide and Ambient Temperature in East Asian Countries: A Time-Stratified Case-Crossover Analysis

Yoonhee Kim, Ho Kim, Yasushi Honda, Yue Leon Guo, Bing-Yu Chen, Jong-Min Woo, and Kristie L. Ebi

Association of Perfluoroalkyl Substances, Bone Mineral Density, and Osteoporosis in the U.S. Population in NHANES 2009–2010

Naila Khalil, Aimin Chen, Miryoung Lee, Stefan A. Czerwinski, James R. Ebert, Jamie C. DeWitt, and Kurunthachalam Kannan

Synergistic and Antagonistic Mutation Responses of Human MCL-5 Cells to Mixtures of Benzo[a]pyrene and 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]pyridine: Dose-Related Variation in the Joint Effects of Common Dietary Carcinogens

Rhiannon David, Timothy Ebbels, and Nigel Gooderham

Occupational Lead Exposure and Associations with Selected Cancers: The Shanghai Men’s and Women’s Health Study Cohorts

Linda M. Liao, Melissa C. Friesen, Yong-Bing Xiang, Hui Cai, Dong-Hee Koh, Bu-Tian Ji, Gong Yang, Hong-Lan Li, Sarah J. Locke, Nathaniel Rothman, Wei Zheng, Yu-Tang Gao, Xiao-Ou Shu, and Mark P. Purdue

Chronic Exposure to Arsenic and Markers of Cardiometabolic Risk: A Cross-Sectional Study in Chihuahua, Mexico

Michelle A. Mendez, Carmen González-Horta, Blanca Sánchez-Ramírez, Lourdes Ballinas-Casarrubias, Roberto Hernández Cerón, Damián Viniegra Morales, Francisco A. Baeza Terrazas, María C. Ishida, Daniela S. Gutiérrez-Torres, R. Jesse Saunders, Zuzana Drobná, Rebecca C. Fry, John B. Buse, Dana Loomis, Gonzalo G. García-Vargas, Luz M. Del Razo, and Miroslav Stýblo

Effects of Crude Oil/Dispersant Mixture and Dispersant Components on PPARγ Activity in Vitro and in Vivo: Identification of Dioctyl Sodium Sulfosuccinate (DOSS; CAS #577-11-7) as a Probable Obesogen

Alexis M. Temkin, Robert R. Bowers, Margaret E. Magaletta, Steven Holshouser, Adriana Maggi, Paolo Ciana, Louis J. Guillette, John A. Bowden, John R. Kucklick, John E. Baatz, and Demetri D. Spyropoulos

Use of the Adaptive LASSO Method to Identify PM2.5 Components Associated with Blood Pressure in Elderly Men: The Veterans Affairs Normative Aging Study

Lingzhen Dai, Petros Koutrakis, Brent A. Coull, David Sparrow, Pantel S. Vokonas, and Joel D. Schwartz

Impact of Exposure Uncertainty on the Association between Perfluorooctanoate and Preeclampsia in the C8 Health Project Population

Raghavendhran Avanasi, Hyeong-Moo Shin, Verónica M. Vieira, David A. Savitz, and Scott M. Bartell

Air Pollution Exposure during Pregnancy and Childhood Autistic Traits in Four European Population-Based Cohort Studies: The ESCAPE Project

Mònica Guxens, Akhgar Ghassabian, Tong Gong, Raquel Garcia-Esteban, Daniela Porta, Lise Giorgis-Allemand, Catarina Almqvist, Aritz Aranbarri, Rob Beelen, Chiara Badaloni, Giulia Cesaroni, Audrey de Nazelle, Marisa Estarlich, Francesco Forastiere, Joan Forns, Ulrike Gehring, Jesús Ibarluzea, Vincent W.V. Jaddoe, Michal Korek, Paul Lichtenstein, Mark J. Nieuwenhuijsen, Marisa Rebagliato, Rémy Slama, Henning Tiemeier, Frank C. Verhulst, Heather E. Volk, Göran Pershagen, Bert Brunekreef, and Jordi Sunyer

Elemental Constituents of Particulate Matter and Newborn’s Size in Eight European Cohorts

Marie Pedersen, Ulrike Gehring, Rob Beelen, Meng Wang, Lise Giorgis-Allemand, Anne-Marie Nybo Andersen, Xavier Basagaña, Claire Bernard, Marta Cirach, Francesco Forastiere, Kees de Hoogh, ,Regina Gražulevičvienė12 Olena Gruzieva, Gerard Hoek, Aleksandra Jedynska, Claudia Klümper, Ingeborg M. Kooter, Ursula Krämer, Jaakko Kukkonen, Daniela Porta, Dirkje S. Postma, Ole Raaschou-Nielsen, Lenie van Rossem, Jordi Sunyer, Mette Sørensen, Ming-Yi Tsai, Tanja G. M. Vrijkotte, Michael Wilhelm, Mark J. Nieuwenhuijsen, Göran Pershagen, Bert Brunekreef, Manolis Kogevinas, and Rémy Slama

Perfluorooctane Sulfonate Concentrations in Amniotic Fluid, Biomarkers of Fetal Leydig Cell Function, and Cryptorchidism and Hypospadias in Danish Boys (1980-1996)

Gunnar Toft, Bo A.G. Jönsson, Jens Peter Bonde, Bent Nørgaard-Pedersen, David M. Hougaard, Arieh Cohen, Christian H. Lindh, Richard Ivell, Ravinder Anand-Ivell, and Morten S. Lindhard

Organochlorine Compounds and Ultrasound Measurements of Fetal Growth in the INMA Cohort (Spain)

Maria-Jose Lopez-Espinosa, Mario Murcia, Carmen Iñiguez, Esther Vizcaino, Olga Costa, Ana Fernández-Somoano, Mikel Basterrechea, Aitana Lertxundi, Mònica Guxens, Mireia Gascon, Fernando Goñi-Irigoyen, Joan O. Grimalt, Adonina Tardón, and Ferran Ballester

A Case–Control Study of Prenatal Thallium Exposure and Low Birth Weight in China

Wei Xia, Xiaofu Du, Tongzhang Zheng, Bin Zhang, Yuanyuan Li, Bryan A. Bassig, Aifen Zhou, Youjie Wang, Chao Xiong, Zhengkuan Li, Yuanxiang Yao, Jie Hu, Yanqiu Zhou, Juan Liu, Weiyan Xue, Yue Ma, Xinyun Pan, Yang Peng, and Shunqing Xu

Erratum


Erratum: “Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother–Child Study (NewGeneris)”

Marie Pedersen, Michelle A. Mendez, Bernadette Schoket, Roger W. Godschalk, Ana Espinosa, Anette Landström, Cristina M. Villanueva, Domenico F. Merlo, Eleni Fthenou, Esther Gracia-Lavedan, Frederik-J. van Schooten, Gerard Hoek, Gunnar Brunborg, Helle M. Meltzer, Jan Alexander, Jeanette K. Nielsen, Jordi Sunyer, John Wright, Katalin Kovács, Kees de Hoogh, Kristine B. Gutzkow, Laura J. Hardie, Leda Chatzi, Lisbeth E. Knudsen, Lívia Anna, Matthias Ketzel, Margaretha Haugen, Maria Botsivali, Mark J. Nieuwenhuijsen, Marta Cirach, Mireille B. Toledano, Rachel B. Smith, Sarah Fleming, Silvia Agramunt, Soterios A. Kyrtopoulos, Viktória Lukács, Jos C. Kleinjans, Dan Segerbäck, and Manolis Kogevinas

Erratum: “Examination of the Safety of Pediatric Vaccine Schedules in a Non-Human Primate Model: Assessments of Neurodevelopment, Learning, and Social Behavior”

Britni Curtis, Noelle Liberato, Megan Rulien, Kelly Morrisroe, Caroline Kenney, Vernon Yutuc, Clayton Ferrier, C. Nathan Marti, Dorothy Mandell, Thomas M. Burbacher, Gene P. Sackett, and Laura Hewitson

Erratum: “Bias in Environmental Cohort Studies: The Example of Bone Lead and Mortality”

Carol Potera


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