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Environmental Health Perspectives

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September 2013 | Volume 121 | Issue 9



Breaking the Mold: New Strategies for Fighting Aflatoxins


Charles W. Schmidt | A270

Aflatoxin B1, the most potent naturally occurring liver carcinogen ever identified, is produced by Aspergillus fungi that infect crops during periods of drought stress and intense heat. Although found around the world, aflatoxins pose a human health threat primarily in developing countries. Researchers and development groups are investigating a variety of new methods to keep these agents out of food supplies.



The Environment Within: Exploring the Role of the Gut Microbiome in Health and Disease

Bacteria in the human gut

Lindsey Konkel | A276

A growing body of research suggests that part of what determines how the human body responds to external stimuli may be not only our own genes but also the genes of the trillions of microorganisms that reside on and in the human body. New studies are shedding light on the ways that microorganisms in the gut influence biological functions and play a role in diseases throughout the body.



Science Selections

Particulate Matter and Cardiovascular Disease: Researchers Turn an Eye toward Microvascular Changes

Julia R. Barrett | A282

Also see Louwies et al., p. 1011

Respiratory Disparity? Obese People May Not Benefit from Improved Air Quality

Carol Potera | A283

Also see Schikowski et al., p. 1034

BPA as a Mammary Carcinogen: Early Findings Reported in Rats

Lindsey Konkel | A284

Also see Acevedo et al., p. 1040

Bias Detection: Study Identifies Instruments for Evaluating Animal Studies

Kellyn S. Betts | A285

Also see Krauth et al., p. 985


Instruments for Assessing Risk of Bias and Other Methodological Criteria of Published Animal Studies: A Systematic Review

David Krauth, Tracey J. Woodruff, and Lisa Bero | 985

Also see Science Selections, p. A285

Human Health Risk Assessment (HHRA) for Environmental Development and Transfer of Antibiotic Resistance

Nicholas J. Ashbolt, Alejandro Amézquita, Thomas Backhaus, Peter Borriello, Kristian K. Brandt, Peter Collignon, Anja Coors, Rita Finley, William H. Gaze, Thomas Heberer, John R. Lawrence, D.G. Joakim Larsson, Scott A. McEwen, James J. Ryan, Jens Schönfeld, Peter Silley, Jason R. Snape, Christel Van den Eede, and Edward Topp  | 993

Current Perspectives on the Use of Alternative Species in Human Health and Ecological Hazard Assessments

Edward J. Perkins, Gerald T. Ankley, Kevin M. Crofton, Natàlia Garcia-Reyero, Carlie A. LaLone, Mark S. Johnson, Joseph E. Tietge, and Daniel L. Villeneuve | 1002


Retinal Microvascular Responses to Short-Term Changes in Particulate Air Pollution in Healthy Adults

Tijs Louwies, Luc Int Panis, Michal Kicinski, Patrick De Boever, and Tim S. Nawrot | 1011

Also see Science Selections, p. A282

A National Prediction Model for PM2.5 Component Exposures and Measurement Error–Corrected Health Effect Inference

Silas Bergen, Lianne Sheppard, Paul D. Sampson, Sun-Young Kim, Mark Richards, Sverre Vedal, Joel D. Kaufman, and Adam A. Szpiro | 1017

Short-term Associations between Fine and Coarse Particulate Matter and Hospitalizations in Southern Europe: Results from the MED-PARTICLES Project

Massimo Stafoggia, Evangelia Samoli, Ester Alessandrini, Ennio Cadum, Bart Ostro, Giovanna Berti, Annunziata Faustini, Benedicte Jacquemin, Cristina Linares, Mathilde Pascal, Giorgia Randi, Andrea Ranzi, Elisa Stivanello, Francesco Forastiere, and the MED-PARTICLES Study Group | 1026

Improved Air Quality and Attenuated Lung Function Decline: Modification by Obesity in the SAPALDIA Cohort

Tamara Schikowski, Emmanuel Schaffner, Flurina Meier, Harish C. Phuleria, Andrea Vierkötter, Christian Schindler, Susi Kriemler, Elisabeth Zemp, Ursula Krämer, Pierre-Olivier Bridevaux, Thierry Rochat, Joel Schwartz, Nino Künzli, and Nicole Probst-Hensch | 1034

Also see Science Selections, p. A283

Perinatally Administered Bisphenol A as a Potential Mammary Gland Carcinogen in Rats

Nicole Acevedo, Barbara Davis, Cheryl M. Schaeberle, Carlos Sonnenschein, and Ana M. Soto | 1040

Also see Science Selections, p. A284

Associations of Urinary Cadmium with Age and Urinary Proteins: Further Evidence of Physiological Variations Unrelated to Metal Accumulation and Toxicity

Agnes Chaumont, Catherine Voisin, Gladys Deumer, Vincent Haufroid, Isabella Annesi-Maesano, Harry Roels, Lutgarde Thijs, Jan Staessen, and Alfred Bernard | 1047

Impact of Geocoding Methods on Associations between Long-term Exposure to Urban Air Pollution and Lung Function

Bénédicte Jacquemin, Johanna Lepeule, Anne Boudier, Caroline Arnould, Meriem Benmerad, Claire Chappaz, Joane Ferran, Francine Kauffmann, Xavier Morelli, Isabelle Pin, Christophe Pison, Isabelle Rios, Sofia Temam, Nino Künzli, Rémy Slama, and Valérie Siroux | 1054

Long-term Exposure to Black Carbon and Carotid Intima-Media Thickness: The Normative Aging Study

Elissa H. Wilker, Murray A. Mittleman, Brent A. Coull, Alexandros Gryparis, Michiel L. Bots, Joel Schwartz, and David Sparrow | 1061

Chronic Arsenic Exposure and Blood Glutathione and Glutathione Disulfide Concentrations in Bangladeshi Adults

Megan N. Hall, Megan Niedzwiecki, Xinhua Liu, Kristin N. Harper, Shafiul Alam, Vesna Slavkovich, Vesna Ilievski, Diane Levy, Abu B. Siddique, Faruque Parvez, Jacob L. Mey, Alexander van Geen, Joseph Graziano, and Mary V. Gamble | 1068

Maternal Stress and Effects of Prenatal Air Pollution on Offspring Mental Health Outcomes in Mice

Jessica L. Bolton, Nicole C. Huff, Susan H. Smith, S. Nicholas Mason, W. Michael Foster, Richard L. Auten, and Staci D. Bilbo | 1075

Children’s Health

Prenatal Nitrate Intake from Drinking Water and Selected Birth Defects in Offspring of Participants in the National Birth Defects Prevention Study

Jean D. Brender, Peter J. Weyer, Paul A. Romitti, Binayak P. Mohanty, Mayura U. Shinde, Ann M. Vuong, Joseph R. Sharkey, Dipankar Dwivedi, Scott A. Horel, Jiji Kantamneni, John C. Huber Jr., Qi Zheng, Martha M. Werler, Katherine E. Kelley, John S. Griesenbeck, F. Benjamin Zhan, Peter H. Langlois, Lucina Suarez, Mark A. Canfield, and the National Birth Defects Prevention Study | 1083

Carotid Intima-Media Thickness and Plasma Asymmetric Dimethylarginine in Mexican Children Exposed to Inorganic Arsenic

Citlalli Osorio-Yáñez, Julio C. Ayllon-Vergara, Guadalupe Aguilar-Madrid, Laura Arreola-Mendoza, Erika Hernández-Castellanos, Angel Barrera-Hernández, Andrea De Vizcaya-Ruiz, and Luz M. Del Razo | 1090

Economic Costs of Childhood Lead Exposure in Low- and Middle-Income Countries

Teresa M. Attina and Leonardo Trasande | 1097

Prenatal Exposure to Persistent Organochlorines and Childhood Obesity in the U.S. Collaborative Perinatal Project

Lea A. Cupul-Uicab, Mark A. Klebanoff, John W. Brock, and Matthew P. Longnecker | 1103



Perspectives of the Development Strategies for a Future Toxicity Testing System in China: Challenges and Opportunities

Bin Zhao | A264

EHP Classic Paper of the Year, 2013

Hugh A. Tilson | A266


Arsenic Levels in Chicken

Tamar Lasky | A 267

Arsenic Levels in Chicken: Nachman et al. Respond

Keeve E. Nachman, Patrick A. Baron, Georg Raber, Kevin A. Francesconi, and David C. Love | A 267

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