Fetal Growth and Prenatal Exposure to Bisphenol A: The Generation R Study

http://dx.doi.org/10.1289/ehp.1205296



Table 3. Univariable and multivariable repeated linear regression analyses between prenatal exposure to BPACB and SD scores of fetal weight and fetal head circumference among 219 pregnant women.
Variable Fetal weight
unadjusted β (95% CI)
Fetal weight
adjusted β (95% CI)
Fetal head circumference
unadjusted β (95% CI)
Fetal head circumference
adjusted β (95% CI)
BPACB, creatinine based total BPA concentration. Beta coefficient represents the average decline/increase in SD score of fetal weight or fetal head circumference per gestational week. The adjusted model contains the following covariates: maternal age, educational level, ethnicity, fetal sex, weight before pregnancy, height at intake, smoking during pregnancy, alcohol use during pregnancy, folic acid use, and parity.
*p < 0.05.
BPACB (μg/g crea) < 1.54 Reference Reference Reference Reference
1.54 < BPACB < 2.51 –0.009 (–0.033, 0.014) –0.010 (–0.033, 0.014) –0.016 (–0.045, 0.013) –0.018 (–0.047, 0.011)
2.51 < BPACB < 4.22 –0.018 (–0.041, 0.006) –0.015 (–0.038, 0.009) –0.019 (–0.047, 0.009) –0.016 (–0.044, 0.013)
> 4.22 –0.001 (–0.024, 0.023) 0.001 (–0.023, 0.025) –0.018 (–0.049, 0.012) –0.016 (–0.047, 0.014)
Per unit increase in BPACB –0.013 (–0.025, –0.001)* –0.011 (–0.023, 0.002) –0.005 (–0.020, 0.009) –0.003 (–0.018, 0.011)