Exposure to Perfluoroalkyl Acids and Markers of Kidney Function among Children and Adolescents Living near a Chemical Plant

http://dx.doi.org/10.1289/ehp.1205838



Table 1. Characteristics of 9,660 study participants < 18 years of age at enrollment into the C8 Health Project.
Characteristic Overall Quartiles of serum PFOA concentrations
1 2 3 4
Measured serum PFOA [ng/mL (range)] 0.7–2071 0.7–< 12.8 12.8–< 28.3 28.3–< 65.4 ≥ 65.4–2,071
Measured serum PFOA [ng/mL (median)] 28.3 9.1 18.6 41.3 139.2
Age [years (mean ± SD)] 12.4 ± 3.8 12.8 ± 3.7 12.6 ± 3.8 12.4 ± 3.8 12.0 ± 3.8
Female [n (%)] 4,684 (48) 1,303 (54) 1,203 (49) 1,144 (47) 1,034 (43)
White [n (%)] 9,346 (97) 2,326 (97) 2,347 (97) 2,349 (97) 2,324 (96)
Ever smoker [n (%)] 92 (1.0) 30 (1.3) 37 (1.5) 18 (0.7) 7 (0.3)
Regular exercise [n (%)] 3,939 (41) 889 (37) 922 (38) 1,068 (44) 1,060 (44)
Household income ≤ $30,000/year [n (%)] 3,679 (48) 1,249 (52) 1,217 (50) 1,089 (45) 1,007 (42)
BMI z-score (mean ± SE) 0.6 ± 1.2 0.63 ± 0.02 0.58 ± 0.03 0.56 ± 0.03 0.51 ± 0.03
eGFR [mL/min/1.73 m2 (mean ± SD)] 133.0 ± 23.9 133.0 ± 24.1 132.6 ± 22.6 133.1 ± 26 133.2 ± 22.9