PFAA | n |
IQR | Model 1^{b} |
Model 2^{c} |
||
---|---|---|---|---|---|---|

Change in eGFR (95% CI) ^{c} |
p-Value |
Change in eGFR (95% CI) ^{c} |
p-Value |
|||

^{a}Expressed as the mean change in eGFR per interquartile range (IQR) increase in each natural log-transformed PFAA.^{b}Model 1: adjusted for age, sex, race, smoking, and household income. ^{c}Model 2: adjusted for model 1 covariates plus regular exercise and BMI z-score. ^{d}First 10 years of life, or current age if < 10 years of age. ^{e}During 3 years before enrollment. ^{f}At time of enrollment (2005–2006). | ||||||

Measured | ||||||

PFOA | 9,660 | 1.63 | –0.75 (–1.41, –0.10) | 0.02 | –0.73 (–1.38, –0.08) | 0.03 |

PFOS | 9,660 | 0.64 | –1.10 (–1.66, –0.53) | 0.0001 | –1.34 (–1.91, –0.77) | < 0.0001 |

PFNA | 9,660 | 0.51 | –0.83 (–1.35, –0.30) | 0.002 | –0.88 (–1.41, –0.36) | 0.001 |

PFHxS | 9,660 | 1.27 | –0.95 (–1.57, –0.32) | 0.003 | –1.02 (–1.64, –0.40) | 0.001 |

Estimated PFOA | ||||||

Early^{d} |
4,787 | 2.10 | –0.03 (–0.99, 0.93) | 0.95 | –0.09 (–1.04, 0.87) | 0.86 |

Recent^{e} |
6,060 | 1.88 | –0.04 (–0.76, 0.68) | 0.91 | –0.06 (–0.77, 0.65) | 0.87 |

Enrollment^{f} |
6,060 | 1.84 | –0.10 (–0.80, 0.60) | 0.78 | –0.12 (–0.81, 0.58) | 0.75 |