Ulcerative Colitis and Perfluorooctanoic Acid (PFOA) in a Highly Exposed Population of Community Residents and Workers in the Mid-Ohio Valley

http://dx.doi.org/10.1289/ehp.1206449



Table 1. Cohort characteristics based on the most recent survey and measured serum PFOA levels in 2005–2006 [n (%)].
Characteristic Community cohort (= 28,541) Worker cohort (= 3,713) Combined cohorts (= 32,254)
aSerum PFOA data for members of the worker cohort are restricted to 1,890 workers who had serum PFOA measurements because of participation in the C8HP in 2005–2006. All other data for workers are from survey data and refer to all 3,713 workers.
Year of birth      
25th percentile 1947 1941 1946
Median 1958 1951 1957
75th percentile 1970 1963 1969
Sex      
Female 16,602 (58) 758 (20) 17,360 (54)
Race/ethnicity      
White, non-Hispanic 27,901 (98) 3,284 (88) 31,185 (97)
Other 640 (2) 134 (4) 774 (2)
Missing 0 295 (8) 295 (1)
BMI (kg/m³)      
< 18.5 414 (2) 38 (1) 452 (1)
18.5–< 25.0 7,693 (27) 972 (26) 8,665 (27)
25.0–< 30.0 9,689 (34) 1,618 (44) 11,307 (35)
≥ 30.0 10,694 (37) 1,057 (29) 11,751 (37)
Education      
< High school 3,026 (11) 37 (1) 3,063 (10)
High school 11,706 (41) 1,265 (34) 12,971 (40)
Some college 9,441 (33) 1,081 (29) 10,522 (33)
≥ College diploma 4,366 (15) 1,328 (36) 5,694 (18)
Missing 2 (< 1) 2 (< 1) 4 (< 1)
Smoking      
Never smoked 13,527 (47) 1,989 (54) 15,516 (48)
Smoked and quit 8,899 (31) 1,297 (35) 10,196 (32)
Smoked, did not quit 6,115 (21) 427 (12) 6,542 (20)
Regular alcohol consumption      
Never 17,011 (60) 1,683 (45) 18,694 (58)
Yes and quit 4,105 (14) 535 (14) 4,640 (14)
Yes, did not quit 7,360 (26) 1,486 (40) 8,846 (27)
In community cohort 28,541 (100) 1,890 (51) 30,431 (94)
Serum PFOA concentration measurement from the C8HP (2005–2006) (ng/mL)a      
Mean 71 325 87
SD 151 921 278
Interquartile range 12–59 56–256 13–68
Median 24 113 26