Design, Methods, and Population for a Study of PFOA Health Effects among Highly Exposed Mid-Ohio Valley Community Residents and Workers

http://dx.doi.org/10.1289/ehp.1206450



Table 2. Community and worker cohort demographics in target and final populations [n (%)].a
  Community cohort Worker cohort Final combined cohort
Target population (= 40,145)b Included in final cohort [= 28,541)c Target population [= 6,026) Included in final cohort [= 3,713)d [= 32,254)
NA, not available.
aDemographic characteristics are as reported on the first survey during 2008–2011, except that information from the 2004–2005 C8HP was used when information was missing from the first survey during 2008–2011. bConsented among those in C8HP of qualifying age. cThe final community cohort included those who had no evidence of working at the plant, responded to at least one survey, and had available serum PFOA concentration estimates. dThe final worker cohort included those who responded to at least one survey and had available serum PFOA concentration estimates. eThe percentage female sex was slightly different from the target population due to exclusion of those who worked at the plant, who were predominantly male.
Year of birth          
< 1920 171 (0.4) 114 (0.4) 416 (6.9) 59 (1.6) 173 (0.5)
1920–1929 1,363 (3.4) 944 (3.3) 532 (8.8) 175 (4.7) 1,119 (3.5)
1930–1939 3,813 (9.5) 2,798 (9.8) 873 (14.5) 552 (14.9) 3,350 (10.4)
1940–1949 6,819 (17.0) 5,067 (17.8) 1,276 (21.2) 974 (26.2) 6,041 (18.7)
1950–1959 8,671 (21.6) 6,480 (22.7) 1,109 (18.4) 840 (22.6) 7,320 (22.7)
1960–1969 8,202 (20.4) 5,728 (20.1) 1,166 (19.3) 723 (19.5) 6,451 (20.0)
1970–1979 6,952 (17.3) 4,674 (16.4) 626 (10.4) 376 (10.1) 5,050 (15.7)
1980–1982 4,154 (10.3) 2,736 (9.6) 28 (0.5) 14 (0.4) 2,750 (8.5)
Known to be deceased 1,254 (3.1) 726 (2.5) 1,189 (19.7) 204 (5.5) 930 (2.9)
Female sex 21,146 (52.7) 16,602 (58.2)e 1,156 (19.2) 758 (20.4) 17,360 (53.8)
Race          
White, non–Hispanic 39,083 (97.4) 27,901 (97.8) NA 3,284 (88.5) 31,185 (96.7)
Other 996 (2.5) 640 (2.2) NA 134 (3.6) 774 (2.4)
Missing 66 (0.2) 0 NA 295 (7.9) 295 (0.9)
Education          
< High school 4,500 (11.2) 3,026 (10.6) NA 37 (1.0) 3,063 (9.5)
High school 16,650 (41.5) 11,706 (41.0) NA 1,265 (34.1) 12,971 (40.2)
Some college 13,298 (33.1) 9,441 (33.1) NA 1,081 (29.1) 10,522 (32.6)
≥ College diploma 5,636 (14.0) 4,366 (15.3) NA 1,328 (35.8) 5,694 (17.7)
Missing 61 (0.2) 2 (0.01) NA 2 (0.1) 4 (0.01)
Smoking          
Never smoked 18,186 (45.3) 13,527 (47.4) NA 1,989 (53.6) 15,516 (48.1)
Smoked and quit 12,276 (30.6) 8,899 (31.2) NA 1,297 (34.9) 10,196 (31.6)
Smoked, did not quit 9,683 (24.1) 6,115 (21.4) NA 427 (11.5) 6,542 (20.3)
Regular alcohol consumption          
Never NA 17,011 (59.6) NA 1,683 (45.3) 18,694 (58.0)
Yes and quit NA 4,105 (14.4) NA 535 (14.4) 4,640 (14.4)
Yes, did not quit NA 7,360 (25.8) NA 1,486 (40.0) 8,846 (27.4)
Missing NA 65 (0.2) NA 9 (0.2) 74 (0.2)
In community cohort 40,145 (100) 28,541 (100) 2,090 (34.7) 1,890 (50.9) 30,431 (94.3)