Maternal Concentrations of Persistent Organochlorine Pollutants and the Risk of Asthma in Offspring: Results from a Prospective Cohort with 20 Years of Follow-up

http://dx.doi.org/10.1289/ehp.1206397



Table 1. Maternal and offspring characteristics of 872 mother–child pairs.
Characteristic Median (10th, 90th percentiles),
mean ± SD, or n (%)
Maternal  
Serum concentration (ng/mL)  
PCB-118 0.17 (0.09, 0.30)
PCB-138 0.74 (0.41, 1.25)
PCB-153 1.37 (0.76, 2.26)
PCB-156 0.10 (0.06, 0.16)
PCB-170 0.37 (0.21, 0.59)
PCB-180 0.67 (0.38, 1.10)
Sum of PCBs (pmol/mL) 9.23 (5.32, 15.11)
HCB 0.54 (0.31, 0.87)
p,p´-DDE 2.47 (1.03, 5.66)
Maternal age at birth (years) 29.0 ± 4.2
Fish intake (g/day) 19.3 ± 15.6
Alcohol (g/day) 2.9 ± 3.8
Maternal cholesterol (mmol/L) 7.3 ± 1.3
Maternal triglycerides (mmol/L) 2.4 ± 0.8
Previous births  
0 500 (57.3)
1 279 (32.0)
≥ 2 93 (10.7)
Cigarettes/day during pregnancy  
0 493 (56.5)
> 0–5 99 (11.4)
> 5 to 15 188 (21.6)
> 15 41 (4.7)
Missing 51 (5.9)
Maternal education  
Elementary school 103 (11.8)
High school or technical school 207 (23.7)
University 296 (33.9)
Higher academic 125 (14.3)
Other education 89 (10.2)
Missing 52 (6.0)
Prepregnancy BMI (kg/m2)  
< 18.5 89 (10.2)
18.5 to < 25 676 (77.5)
25 to < 30 53 (6.1)
> 30 23 (2.6)
Missing 31 (3.6)
Offspring  
Registry-based diagnoses (= 872)  
Asthma medication 111 (12.7)
Asthma hospitalization 32 (3.7)
Self-reported diagnoses (= 654)  
Lifetime doctor diagnosis 89 (13.6)
Current asthma medication use 48 (7.3)
Birth weight (g) 3493.7 ± 579.9
Gestational age (days) 282.3 ± 11.8
Boys 461 (52.9)
Age at follow-up (years) 19.6 ± 0.49