Associations of Filaggrin Gene Loss-of-Function Variants with Urinary Phthalate Metabolites and Testicular Function in Young Danish Men

http://dx.doi.org/10.1289/ehp.1306720



Table 1. “Parent” phthalate diesters to which humans are exposed, and their metabolites that are measurable in urine.
Phthalate group Parent phthalate diesters Measurable urinary metabolites LOD
(ng/mL)
Abbreviations: LMW, low-molecular-weight phthalates (often found in personal care products); HMW, high-molecular-weight phthalates (used as plasticizers; infrequently found in personal care products).
aMCPP is a metabolite of DOP, and is also a minor metabolite of diisooctyl phthalate, diisodecyl phthalate, DiNP, DEHP, BBzP and DBP (dibutyl phthalate).
LMW DEP Diethyl phthalate MEP Monoethyl phthalate 0.46
DnBP Di-n-butyl phthalate MnBP Mono-n-butyl phthalate 0.57
DiBP Diisobutyl phthalate MiBP Monoisobutyl phthalate 0.55
BBzP Butylbenzyl phthalate MBzP Monobenzyl phthalate 0.25
HMW DEHP Di(2-ethylhexyl) phthalate MEHP Mono(2-ethylhexyl) phthalate 0.63
MEHHP Mono(2-ethyl-5-hydroxyhexyl) phthalate 0.30
MEOHP Mono(2-ethyl-5-oxohexyl) phthalate 0.30
MECPP Mono(2-ethyl-5-carboxypentyl) phthalate 0.17
DOP Dioctyl phthalate MOP Mono-n-octyl phthalate 0.15
MCPPa Mono-3-carboxypropyl phthalate 0.14
DiNP Diisononyl phthalate MiNP Mono-isononyl phthalate 0.15
MHiNP Mono(hydroxy-isononyl) phthalate 0.12
MOiNP Mono(oxo-isononyl) phthalate 0.11
MCiOP Mono(carboxy-isononyl) phthalate 0.05