Prenatal Polybrominated Diphenyl Ether Exposures and Neurodevelopment in U.S. Children through 5 Years of Age: The HOME Study

http://dx.doi.org/10.1289/ehp.1307562



Table 3. Estimated ORs (95% CIs) of having cognitive and behavior rating scores 1 SD from the population mean at ages 1–5 years by a 10-fold increase in maternal BDE-47 concentrations.
Age (years) MDI/FSIQ < 85 Externalizing Problems ≥ 60 Hyperactivity subscale ≥ 60 Behavioral Symptoms Index ≥ 60
n (%) OR (95% CI) n (%) OR (95% CI) n (%) OR (95% CI) n (%) OR (95% CI)
Adjusted for maternal age at enrollment, race, education, marital status, maternal serum cotinine concentrations at enrollment, maternal IQ, child sex, maternal depression, household income, and HOME Inventory score.
1 52 (18.25) 1.22 (0.51, 2.91)
2 78 (32.64) 0.83 (0.39, 1.78) 12 (5.00) 5.86 (2.21, 15.55) 28 (11.67) 3.06 (1.17, 7.98) 14 (5.83) 1.30 (0.44, 3.84)
3 51 (23.18) 1.76 (0.78, 3.99) 37 (16.30) 2.13 (0.99, 4.56) 33 (14.54) 2.68 (1.17, 6.16) 32 (14.10) 2.54 (1.08, 5.98)
4 17 (10.30) 1.51 (0.44, 5.21) 17 (10.30) 2.22 (0.55, 9.01) 13 (7.88) 2.02 (0.49, 8.39)
5 25 (13.97) 1.70 (0.36, 7.94) 17 (9.29) 2.66 (0.47, 15.06) 19 (10.38) 4.45 (1.31, 15.14) 16 (8.74) 4.80 (1.19, 19.26)