Traffic-Related Air Pollution and Dementia Incidence in Northern Sweden: A Longitudinal Study

http://dx.doi.org/10.1289/ehp.1408322



Table 3. Hazard ratios (HRs) and 95% confidence intervals (CIs) for dementia in association with baseline annual NOx concentration from Cox proportional hazards models (sample 2 excluded).
NOxa (μg/m3) n (person-years) Cases HR (95% CI)
aThe annual non–back-extrapolated NOx baseline concentration at the residence of each participant was used as a proxy for exposure to air pollution. bModel 1: age-adjusted. cModel 2: adjusted for education, physical activity, smoking, sex, BMI (body mass index), WHR (waist–hip ratio), alcohol, age, and ApoE4.
Model 1b
4.8–9 262 (3,065) 32 1.0
> 9–17 317 (3,793) 45 1.24 (0.79, 1.96)
> 17–26 320 (3,625) 57 1.49 (0.97, 2.30)
> 26 315 (3,172) 67 1.72 (1.13, 2.62)
Per 10 μg/m3 1.05 (0.98, 1.13)
Model 2c
4.8–9 227 (2,757) 27 1.0
> 9–17 275 (3,423) 40 1.39 (0.85, 2.28)
> 17–26 285 (3,294) 52 1.58 (0.98, 2.53)
> 26 278 (2,821) 62 1.71 (1.08, 2.73)
Per 10 μg/m3 1.08 (1.00, 1.16)