Flavoring Chemicals in E-Cigarettes: Diacetyl, 2,3-Pentanedione, and Acetoin in a Sample of 51 Products, Including Fruit-, Candy-, and Cocktail-Flavored E-Cigarettes

http://dx.doi.org/10.1289/ehp.1510185



Table 2. Estimated mass of flavoring chemicals in e-cigarettes (μg/e-cigarette).
Flavor Brand Flavor type Diacetyl (2,3-butanedione) 2,3-Pentanedione Acetoin
< LOQ: detected by the laboratory above the laboratory limit of detection (LOD) but less than the limit of quantification (LOQ); LOQ by batch 1 and batch 2 (diacetyl: 2.3 μg, 0.19 μg; 2,3-pentanedione: 0.07 μg, 0.38 μg; acetoin: 1.08 μg, 3.2 μg). < LOD: not detected above the laboratory limit of detection (LOD), 0.05 μg.
Classic A Tobacco 3.9 1.0 37.5
Classic A Tobacco < LOD < LOD < LOD
Menthol A Other < LOD < LOD < LOD
Menthol B Other < LOD < LOD < LOD
Original B Tobacco < LOD < LOD < LOD
Cherry Crush C Fruit < LOQ < LOD 9.0
Cherry Crush C Fruit 14.7 3.4 165.6
Classic C Tobacco < LOQ 0.8 18.1
Java Jolt C Brown 21.5 7.4 212
Menthol C Other 8.3 2.7 18.3
Peach Schnapps C Cocktail 238.9 64.4 529.2
Pina Colada C Cocktail 27.0 7.1 45.5
Pina Colada C Cocktail 1.6 < LOD 130
Pina Colada C Cocktail < LOD < LOD < LOD
Pina Colada C Cocktail < LOD < LOD 16.5
Vanilla C Brown < LOD 0.9 < LOD
Bold D Tobacco 5.9 < LOD 39.8
Gold D Tobacco 0.6 < LOD 7.0
Menthol D Other 4.9 < LOQ 9.6
Pomegranate D Fruit < LOD 0.2 11.9
Pomegranate D Fruit 6.9 < LOD 41.4
Vanilla Bean D Brown 6.7 < LOD 13.1
Bad Apple E Fruit 6.0 < LOD < LOQ
Banana E Fruit < LOD < LOD < LOQ
Cin E Other 38.4 23.4 < LOQ
Iced Berry E Fruit 6.6 < LOD 33.4
Iced Berry E Fruit 2.6 < LOD 17.3
Just Guava E Fruit < LOQ < LOD 7.3
Kick! E Brown 20.0 < LOD 19.1
Lime and Coconut E Fruit 10.3 < LOD 77.9
Peach Pit E Fruit < LOD < LOD 6.1
Snap! E Brown 10.9 3.4 88.2
Strawberry E Fruit < LOQ < LOD 5.2
Cherry F Fruit 4.2 < LOD 35.6
Double Apple Hookah F Fruit 21.1 2.3 193.5
Franks Lemon Lime F Fruit 4.2 1.1 47.3
Grape Hookah F Fruit 1.5 1.6 27.9
Orange Mint F Fruit 1.1 1.5 27.9
Peach F Fruit 8.3 < LOD 117.5
Pina Colada F Cocktail 11.6 0.7 55.8
Watermelon F Fruit 13.3 1.4 224.3
Watermelon F Fruit 7.4 < LOD 72.5
Bluewater Punch G Fruit < LOD < LOD 3.8
Cherry Lava G Fruit < LOD < LOD 5.6
CooCoo Coconut G Brown 1.0 < LOD 19.5
Milk Chocolate G Dairy < LOD < LOD 9.7
Pineapple Punch G Fruit < LOD < LOD 10.4
Waikiki Watermelon G Fruit 4.4 < LOQ 2.1
Alien Blood H Fruit 0.4 < LOD 19.4
Carmel Popcorn H Brown 0.3 < LOD 1.5
Cupcake H Brown 0.3 4.6 1.3
Energy Drink H Other < LOD < LOD 12.2
Fruit Squirts H Fruit 0.9 < LOD 114.4
Oatmeal Cookie H Other 2.2 4.2 26.1
Bubble Gum I Other < LOD < LOD < LOD
Cheesecake I Dairy 0.9 < LOD < LOD
Cola I Brown < LOQ 0.2 3.7
Cotton Candy I Fruit 0.8 < LOD 8
Tutti Frutti I Fruit 9.3 0.8 24.7